Abstract 4782: STACT: A novel tumor-targeting, systemically-administered delivery platform capable of targeting intractable pathways and precise immunomodulation of the tumor microenvironment
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DOI: 10.1158/1538-7445.sabcs18-4782
Abstract: We have engineered a tumor-targeted, microbial immunotherapy platform called STACT (S almonella T yphimurium (Attenuated) and Checkpoint Therapy). The platform strain has been engineered to increase tumor-specific enrichment, reduce immunosuppressive inflammation and enhance tolerability. Upon… read more here.
Keywords: platform strain; tumor microenvironment; platform; tumor ... See more keywords
Comparative genomic analysis of Methylocystis sp. MJC1 as a platform strain for polyhydroxybutyrate biosynthesis
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DOI: 10.1371/journal.pone.0284846
Abstract: Biodegradable polyhydroxybutyrate (PHB) can be produced from methane by some type II methanotroph such as the genus Methylocystis. This study presents the comparative genomic analysis of a newly isolated methanotroph, Methylocystis sp. MJC1 as a… read more here.
Keywords: methylocystis mjc1; analysis; methylocystis; platform strain ... See more keywords