Targeted siRNA nanocarrier: a platform technology for cancer treatment
Sign Up to like & getrecommendations! Published in 2022 at "Oncogene"
DOI: 10.1038/s41388-022-02241-w
Abstract: The small arginine-rich protein protamine condenses complete genomic DNA into the sperm head. Here, we applied its high RNA binding capacity for spontaneous electrostatic assembly of therapeutic nanoparticles decorated with tumour-cell-specific antibodies for efficiently targeting… read more here.
Keywords: cancer; antibody protamine; treatment; platform technology ... See more keywords
A platform technology for generating subunit vaccines against diverse viral pathogens
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.963023
Abstract: The COVID-19 pandemic response has shown how vaccine platform technologies can be used to rapidly and effectively counteract a novel emerging infectious disease. The speed of development for mRNA and vector-based vaccines outpaced those of… read more here.
Keywords: platform technology; clamp; subunit vaccines; mers cov ... See more keywords