Articles with "platforms complementary" as a keyword



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Complementary epitopes and favorable developability of monoclonal anti-LAMP1 antibodies generated using two transgenic animal platforms

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Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0235815

Abstract: Monoclonal antibodies (mAbs) for therapeutic applications should be as similar to native human antibodies as possible to minimize their immunogenicity in patients. Several transgenic animal platforms are available for the generation of fully human mAbs.… read more here.

Keywords: developability; transgenic animal; animal platforms; platforms complementary ... See more keywords