Advances in Ovarian Cancer Care and Unmet Treatment Needs for Patients With Platinum Resistance: A Narrative Review.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2023.0197
Abstract: Importance Platinum-based chemotherapy has been the standard of care for ovarian cancer for the past 3 decades. Although most patients respond to platinum-based treatment, emergence of platinum resistance in recurrent ovarian cancer is inevitable during… read more here.
Keywords: platinum resistant; ovarian cancer; treatment; resistant ovarian ... See more keywords
EGFR and Prion protein promote signaling via FOXO3a‐KLF5 resulting in clinical resistance to platinum agents in colorectal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12411
Abstract: Epidermal growth factor receptor (EGFR) supports colorectal cancer progression via oncogenic signaling. Anti‐EGFR therapy is being investigated as a clinical option for colorectal cancer, and an observed interaction between EGFR and Prion protein has been… read more here.
Keywords: egfr; platinum; colorectal cancer; resistance ... See more keywords
Recent advances of platinum-based anticancer complexes in combinational multimodal therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300253
Abstract: Platinum drugs with manifest therapeutic effects are widely used, but their systemic toxicity and the drug resistance acquired by cancer cells limit their clinical applications. Thus, the exploration on appropriate methods and strategies to overcome… read more here.
Keywords: anticancer complexes; based anticancer; therapy; platinum drugs ... See more keywords
Single-Junction Polymer Solar Cells with 16.35% Efficiency Enabled by a Platinum(II) Complexation Strategy.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201901872
Abstract: A new strategy of platinum(II) complexation is developed to regulate the crystallinity and molecular packing of polynitrogen heterocyclic polymers, optimize the morphology of the active blends, and improve the efficiency of the resulting nonfullerene polymer… read more here.
Keywords: platinum; polymer; bis; efficiency ... See more keywords
Rational Design of Platinum–Bismuth Sulfide Schottky Heterostructure for Sonocatalysis‐Mediated Hydrogen Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202209589
Abstract: Conventional sonodynamic therapy is unavoidably limited by the tumor microenvironment, although many sonosensitizers have been developed to improve them to a certain extent. Given this, a concept of sonocatalytic hydrogen evolution is proposed, which is… read more here.
Keywords: bismuth sulfide; sonocatalysis mediated; therapy; platinum ... See more keywords
Highly Efficient Electrocatalytic Hydrogen Production over Carbon Nanotubes Loaded with Platinum Nanoparticles Using Solution Processing
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.202300094
Abstract: Proton exchange membrane (PEM) electrolyzers are used for hydrogen (H2) production by water electrolysis. The commercial cathodic electrocatalyst for this process is typically mechanically mixed platinum on carbon (Pt/C). However, aggregation of the platinum (Pt)… read more here.
Keywords: carbon; hydrogen production; highly efficient; loaded platinum ... See more keywords
A New Platinum‐Like Efficient Electrocatalyst for Hydrogen Evolution Reaction at All pH: Single‐Crystal Metallic Interweaved V8C7 Networks
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Energy Materials"
DOI: 10.1002/aenm.201800575
Abstract: DOI: 10.1002/aenm.201800575 reaction (HER) has been identified as a promising technology for hydrogen production.[3] Generally, platinum is normally working as HER electrocatalyst for its high catalytic activity and stability at various pH values (0–14).[4,5] Unfortunately,… read more here.
Keywords: platinum; v8c7 networks; reaction; platinum like ... See more keywords
A pronounced ligand effect on platinum‐catalyzed Hydrosilylation of terminal alkynes
Sign Up to like & getrecommendations! Published in 2018 at "Applied Organometallic Chemistry"
DOI: 10.1002/aoc.4037
Abstract: The use of ligands to tune the reactivity and regioselectivity of transition metal-based catalyst for silicon-mediated organic synthesis (SiMOS) is an important topic and challenge in organosilicon chemistry and synthetic organic chemitstry. In this manuscript,… read more here.
Keywords: platinum; pronounced ligand; chemistry; ligand effect ... See more keywords
ONC201 induces the unfolded protein response (UPR) in high‐ and low‐grade ovarian carcinoma cell lines and leads to cell death regardless of platinum sensitivity
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Medicine"
DOI: 10.1002/cam4.3858
Abstract: Treatment of both platinum resistant high grade (HG) and low‐grade (LG) ovarian cancer (OVCA) poses significant challenges as neither respond well to conventional chemotherapy leading to morbidity and mortality. Identification of novel agents that can… read more here.
Keywords: platinum; unfolded protein; grade ovarian; low grade ... See more keywords
Reactivity of TiO2 Nanotube‐Supported Platinum Particles in the CO Oxidation Reaction
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DOI: 10.1002/cctc.201600913
Abstract: The CO oxidation on different platinum model catalysts, in particular differently sized Pt particles on vertically aligned TiO2 nanotubes (d=80, l=200 nm) was investigated by near‐ambient‐pressure X‐ray photoelectron spectroscopy and simultaneous online gas analysis. The results… read more here.
Keywords: tio2; platinum; reactivity; reaction ... See more keywords
Active Site Elucidation and Optimization in Pt Co‐catalysts for Photocatalytic Hydrogen Production over Titania
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DOI: 10.1002/cctc.201700901
Abstract: Platinum co‐catalysts play a critical role in promoting the photocatalytic performance of inorganic semiconductors, yet despite intensive investigation, the active platinum species responsible remains controversial. Here, the physicochemical properties of Pt nanoparticles introduced into anatase… read more here.
Keywords: platinum; production; photocatalytic hydrogen; spectroscopy ... See more keywords