Recent advances of platinum-based anticancer complexes in combinational multimodal therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300253
Abstract: Platinum drugs with manifest therapeutic effects are widely used, but their systemic toxicity and the drug resistance acquired by cancer cells limit their clinical applications. Thus, the exploration on appropriate methods and strategies to overcome… read more here.
Keywords: anticancer complexes; based anticancer; therapy; platinum drugs ... See more keywords
Thermally Activated Delayed Phosphorescence and Interchromophore Exciton Coupling in a Platinum‐Based Organometallic Emitter
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Optical Materials"
DOI: 10.1002/adom.202001023
Abstract: The comprehension of triplet exciton mechanisms in organic–inorganic semiconductors has a significant impact on emerging optoelectronic and biosensing technologies. The capability to mutually integrate the photophysical properties of conjugated organic semiconductor with those of well‐characterized… read more here.
Keywords: delayed phosphorescence; thermally activated; platinum based; interchromophore exciton ... See more keywords
LINC00857 expression predicts and mediates the response to platinum‐based chemotherapy in muscle‐invasive bladder cancer
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DOI: 10.1002/cam4.1570
Abstract: Approximately 20% of patients with bladder cancer are diagnosed with muscle‐invasive disease (MIBC). The treatment involves radical cystectomy, but almost 50% of patients with MIBC eventually relapse and develop metastasis. The use of platinum‐based chemotherapy… read more here.
Keywords: chemotherapy; bladder cancer; platinum based; based chemotherapy ... See more keywords
Maintenance treatment with rucaparib for recurrent ovarian carcinoma in ARIEL3, a randomized phase 3 trial: The effects of best response to last platinum‐based regimen and disease at baseline on efficacy and safety
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DOI: 10.1002/cam4.4260
Abstract: The efficacy and safety of rucaparib maintenance treatment in ARIEL3 were evaluated in subgroups based on best response to most recent platinum‐based chemotherapy and baseline disease. read more here.
Keywords: efficacy safety; maintenance treatment; best response; platinum based ... See more keywords
Comparative survival analysis of platinum‐based adjuvant chemotherapy for early‐stage squamous cell carcinoma and adenocarcinoma of the lung
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DOI: 10.1002/cam4.4570
Abstract: Although cytotoxic platinum‐based adjuvant chemotherapy (pACT) has been recommended for patients with completely resected early‐stage (ES) non–small‐cell lung cancer (ES‐NSCLC), therapeutic regimens for NSCLC have evolved in the past two decades. The study was aimed… read more here.
Keywords: cell; based adjuvant; early stage; squamous cell ... See more keywords
The Application of Biomaterials in the Treatment of Platinum‐Resistant Ovarian Cancer
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DOI: 10.1002/cmdc.201900450
Abstract: More than 70 % of women with ovarian cancer are diagnosed with advanced‐stage disease, which is initially treated with cytoreductive surgery, and combination chemotherapy with platinum‐based compounds. Most patients initially respond to platinum‐based therapy, but eventually… read more here.
Keywords: resistant ovarian; platinum; platinum based; ovarian cancer ... See more keywords
Genetic variation in the DNA repair pathway as a potential determinant of response to platinum‐based chemotherapy in breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26091
Abstract: Platinum‐based chemotherapy is often used as a first‐line treatment for patient with breast cancer. Platinum agents bind to DNA, forming adducts that contain intra and inter‐strand crosslinks. It is possible that genetic variations of the… read more here.
Keywords: chemotherapy; platinum; dna repair; platinum based ... See more keywords
Immunotherapy for Urothelial Carcinoma: Current Evidence and Future Directions
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DOI: 10.1007/s11934-018-0851-7
Abstract: Purpose of ReviewUntil recently, effective treatment options for patients with advanced urothelial carcinoma were limited to platinum-based chemotherapy. In the post-platinum setting and for patients ineligible for cisplatin, minimally effective second-line chemotherapy was used and… read more here.
Keywords: based chemotherapy; platinum based; carcinoma; urothelial carcinoma ... See more keywords
Rechallenge treatment with a platinum-based regimen in patients with sensitive relapsed small-cell lung cancer
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DOI: 10.1007/s12032-018-1123-6
Abstract: Among patients with relapsed small-cell lung cancer (SCLC), those who relapse > 90 days after first-line chemotherapy are classified sensitive relapse. Rechallenge with a first-line platinum-based regimen has been used in sensitive relapsed SCLC patients, but its importance… read more here.
Keywords: chemotherapy; platinum based; line; rechallenge ... See more keywords
Defect-density control of platinum-based nanoframes with high-index facets for enhanced electrochemical properties
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DOI: 10.1007/s12274-019-2530-5
Abstract: Structure-engineered platinum-based nanoframes (NFs) at the atomic level can effectively improve the catalytic performance for fuel cells and other heterogeneous catalytic fields. We report herein, a microwave-assisted wet-chemical method for the preparation of platinum-copper-cobalt NFs… read more here.
Keywords: platinum based; index facets; high index; density ... See more keywords
Genome-wide analysis identify novel germline genetic variations in ADCY1 influencing platinum-based chemotherapy response in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2021 at "Acta Pharmaceutica Sinica B"
DOI: 10.1016/j.apsb.2021.10.007
Abstract: Abstract To explore the pharmacogenomic markers that affect the platinum-based chemotherapy response in non-small-cell lung carcinoma (NSCLC), we performed a two-cohort of genome-wide association studies (GWAS), including 34 for WES-based and 433 for microarray-based analyses,… read more here.
Keywords: based chemotherapy; chemotherapy response; platinum based;