Development of Clioquinol Platinum(IV) Conjugates as Autophagy-Targeted Antimetastatic Agents.
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DOI: 10.1021/acs.jmedchem.2c01895
Abstract: A series of autophagy-targeted antimetastatic clioquinol (CLQ) platinum(IV) conjugates were designed and prepared by incorporating an autophagy activator CLQ into the platinum(IV) system. Complex 5 with the cisplatin core bearing dual CLQ ligands with potent… read more here.
Keywords: autophagy targeted; targeted antimetastatic; platinum conjugates; platinum ... See more keywords