Synthesis of Platinum-Containing Conjugated Polymers Bearing Optically Active Amide Groups: A Mechanistic Study of Chiral Aggregation
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DOI: 10.1021/acs.macromol.0c00911
Abstract: Chirally regulated π-conjugated polymers containing platinum (Pt) complex moieties have great potential as chiroptically functional materials. In this study, novel platinum-containing conjugated po... read more here.
Keywords: containing conjugated; platinum; conjugated polymers; platinum containing ... See more keywords
Dostarlimab for the treatment of advanced endometrial cancer
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2022.2044791
Abstract: ABSTRACT Introduction Between 20% and 30% of the endometrial cancers (EC) are associated with a deficiency of a mismatch repair (MMRd) protein or high microsatellite instability (MSI-H), characteristics that render the tumor more sensitive to… read more here.
Keywords: dostarlimab; platinum containing; treatment advanced; containing regimen ... See more keywords
Multi-institutional prospective study of nedaplatin plus S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-containing regimens
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DOI: 10.1177/1758834016675099
Abstract: Background: In this multi-institutional prospective study, we aimed to assess the safety and efficacy of nedaplatin plus S-1 (NS) chemotherapy for patients with recurrent and metastatic nasopharyngeal carcinoma (NPC) when platinum-containing regimens failed. Methods: A… read more here.
Keywords: recurrent metastatic; multi institutional; institutional prospective; prospective study ... See more keywords
A randomized, double-blind, multicenter phase III study evaluating paclitaxel with and without RAD001 in patients with gastric cancer who have progressed after therapy with a fluoropyrimidine/platinum-containing regimen (RADPAC).
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.4_suppl.4
Abstract: 4Background: There is a need for effective treatments in the second- or further line setting in advanced gastric cancer, especially for new agents. In the current trial we evaluated paclitaxel with RAD001 (everolimus) in patients… read more here.
Keywords: fluoropyrimidine platinum; containing regimen; rad001; platinum containing ... See more keywords
Oxidative Status as an Attribute for Selective Antitumor Activity of Platinum-Containing Nanoparticles against Hepatocellular Carcinoma
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DOI: 10.3390/ijms232314773
Abstract: Overcoming the limitations for efficient and selective drug delivery is one of the most challenging obstacles for newly designed anticancer agents. In this study, we present two types of platinum-based nanoparticles (NP), ultrasmall 2 nm… read more here.
Keywords: containing nanoparticles; oxidative status; platinum containing; status ... See more keywords