Clinical benefit of platinum doublet combination therapy in older adults with advanced non-small cell lung cancer: A prospective multicenter study by the National Hospital Organization in Japan.
Sign Up to like & getrecommendations! Published in 2023 at "Thoracic cancer"
DOI: 10.1111/1759-7714.14904
Abstract: BACKGROUND Previous trials suggest that older adults with non-small cell lung cancer (NSCLC) derive benefit from platinum doublet combination therapy, but its superiority is controversial. Although geriatric assessment variables are used to assess the individual… read more here.
Keywords: platinum doublet; combination; doublet combination; combination therapy ... See more keywords
A Recurrent Platinum Refractory Ovarian Cancer Patient With a Partial Response After RRx-001 Resensitization to Platinum Doublet
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DOI: 10.1177/2324709618760080
Abstract: This case report describes the clinical course of a heavily pretreated patient enrolled on the Phase II QUADRUPLE THREAT clinical trial (NCT02489903) with recurrent metastatic epithelial ovarian cancer that was previously treated with a platinum… read more here.
Keywords: platinum doublet; rrx 001; platinum; ovarian cancer ... See more keywords
Neoadjuvant treatment of pembrolizumab plus platinum-doublet chemotherapy in stage IIIA squamous cell carcinoma of the lung: a case report.
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DOI: 10.21037/apm-21-335
Abstract: With the popularity of neoadjuvant therapy as first-line treatment, especially for advanced squamous cell carcinoma (SCC), the focus has become accurate individualized treatment. Specifically, toxic side effects of traditional platinum-doublet chemotherapy are high, so treatment… read more here.
Keywords: chemotherapy; platinum doublet; treatment; doublet chemotherapy ... See more keywords
New prognostic model for patients with advanced gastric cancer: Fluoropyrimidine/platinum doublet for first-line chemotherapy
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DOI: 10.3748/wjg.v27.i48.8357
Abstract: BACKGROUND New prognostic factors have been reported in patients with metastatic or recurrent gastric cancer (MRGC), necessitating modifications to the previous prognostic model. AIM To develop a new model, MRGC patients who received fluoropyrimidines/ platinum… read more here.
Keywords: prognostic model; platinum doublet; model; gastric cancer ... See more keywords
Feasibility and safety of platinum-doublet therapy in patients with small-cell lung cancer in the third-line setting: A multi-institutional retrospective study
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DOI: 10.3892/ol.2022.13488
Abstract: Small-cell lung cancer (SCLC) is a highly malignant tumor, and no standard third-line therapy has been established. The present study retrospectively analyzed the efficacy and safety of platinum-based regimens in patients with third-line SCLC who… read more here.
Keywords: third line; platinum doublet; safety platinum; single agent ... See more keywords
Maintenance Therapy with Pembrolizumab after Platinum-Doublet Chemotherapy Leading to Hyperprogression in a Patient with Metastatic Bladder Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Asia-Pacific Journal of Oncology Nursing"
DOI: 10.4103/apjon.apjon-2142
Abstract: The anti-programmed cell death receptor 1 (anti-PD-1) immunotherapy has been recommended in several treatment scenarios of metastatic urothelial cancer (UC), including as a maintenance therapy after first-line chemotherapy. However, the PD-1 inhibitor accelerates tumor growth… read more here.
Keywords: platinum doublet; maintenance; maintenance therapy; doublet chemotherapy ... See more keywords
Efficacy, safety, and prognostic factors of apatinib plus platinum doublet chemotherapy in advanced non-small cell lung cancer
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DOI: 10.4103/jcrt.jcrt_1853_21
Abstract: Background: Anti-angiogenesis drugs are applicable in treating advanced non-small cell lung cancer (NSCLC); however, the related data regarding apatinib, a Chinese domestic anti-vascular endothelial growth factor receptor-2 (VEGFR-2) production, are limited. Therefore, this study explored… read more here.
Keywords: apatinib plus; plus platinum; doublet chemotherapy; platinum doublet ... See more keywords
Predictive significance of inflammatory indexes in metastatic nonsmall cell lung cancer patients treated with platinum-doublet chemotherapy
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DOI: 10.4103/jcrt.jcrt_1902_20
Abstract: Introduction: Lung cancer is the leading cause of cancer-related deaths, worldwide. Despite immune checkpoint inhibitors and targeted therapy have revolutionized the treatment of metastatic nonsmall cell lung cancer (NSCLC), a significant proportion of patients are… read more here.
Keywords: doublet chemotherapy; platinum doublet; patients treated; chemotherapy ... See more keywords