EGFR mutation analysis for prospective patient selection in AURA3 phase III trial of osimertinib versus platinum-pemetrexed in patients with EGFR T790M-positive advanced non-small-cell lung cancer.
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DOI: 10.1016/j.lungcan.2018.10.027
Abstract: OBJECTIVES In AURA3 (NCT02151981), osimertinib treatment provided significant clinical benefit compared with platinum-pemetrexed in patients with epidermal growth factor receptor (EGFR) T790M-positive advanced non-small-cell lung cancer (NSCLC), whose tumors had progressed on previous EGFR-tyrosine kinase… read more here.
Keywords: t790m positive; platinum pemetrexed; egfr mutation; positive advanced ... See more keywords
Successful treatment of pulmonary inflammatory myofibroblastic tumor with platinum‐pemetrexed: The first report of two cases
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DOI: 10.1111/1759-7714.13520
Abstract: Pulmonary inflammatory myofibroblastic tumor (IMT) is a rare tumor. Here, we report two cases of pulmonary IMT successfully treated with platinum and pemetrexed. The results from this study suggest that platinum‐pemetrexed might be an effective… read more here.
Keywords: tumor; platinum pemetrexed; myofibroblastic tumor; pulmonary inflammatory ... See more keywords