Single‐cell RNA‐seq analysis reveals the platinum resistance gene COX7B and the surrogate marker CD63
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1828
Abstract: Cancers acquire resistance to systemic treatment with platinum‐based chemotherapy (eg, cisplatin [CDDP]) as a result of a dynamic intratumoral heterogeneity (ITH) and clonal repopulation. However, little is known about the influence of chemotherapy on ITH… read more here.
Keywords: platinum resistance; resistance; gene cox7b; cancer ... See more keywords
Type 3 Non-uniqueness in Interpolations Using Standard Platinum Resistance Thermometers Between − 196 °C and 100 °C
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DOI: 10.1007/s10765-019-2560-y
Abstract: This paper reports on precise measurements of the non-uniqueness (interpolation errors) associated with using Standard Platinum Resistance Thermometers (SPRTs) in the range from − 196 °C to 100 °C. Six long-stem SPRTs were compared with unprecedented ( read more here.
Keywords: platinum resistance; resistance thermometers; non uniqueness; standard platinum ... See more keywords
Standard platinum resistance thermometer interpolations in a revised temperature scale
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DOI: 10.1088/1681-7575/ab6b3c
Abstract: The thermal metrology community is considering revising the International Temperature Scale of 1990 (ITS-90), motivated by the opportunity to improve the thermodynamic accuracy, reproducibility, and ease of use of the scale, as well as health… read more here.
Keywords: platinum resistance; standard platinum; temperature scale; resistance ... See more keywords
DNA methylome profiling identifies novel methylated genes in epithelial ovarian cancer patients with platinum resistance
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Obstetrics and Gynaecology Research"
DOI: 10.1111/jog.14634
Abstract: Platinum‐based chemotherapy is widely used for epithelial ovarian cancer (EOC). As high as 20–25% of EOC patients will not respond to the initial chemotherapy. Accumulated evidences have implied that DNA methylation may serve as a… read more here.
Keywords: platinum resistance; dna methylome; epithelial ovarian; ovarian cancer ... See more keywords
THSD7B Mutation Induces Platinum Resistance in Small Cell Lung Cancer Patients
Sign Up to like & getrecommendations! Published in 2022 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s363665
Abstract: Aim Several cases of small cell lung cancer (SCLC) patients demonstrate resistance to the treatment initiatives such as cisplatin after platinum chemotherapy. It is crucial to the improvement of the overall survival (OS) of SCLC… read more here.
Keywords: platinum resistance; cell; thsd7b mutation; resistance ... See more keywords
MiR-320b and miR-320d as Biomarkers to Predict and Participate in the Formation of Platinum Resistance in Ovarian Cancer Patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.881496
Abstract: Patients with ovarian cancer who receive platinum-based chemotherapy typically develop platinum resistance, which leads to tumor recurrence and mortality. Therefore, finding the underlying mechanisms and biomarkers is critical. A total of 51 platinum-resistant and 70… read more here.
Keywords: platinum resistance; platinum; ovarian cancer; mir ... See more keywords
Platinum-Resistant Ovarian Cancer Is Vulnerable to the cJUN-XRCC4 Pathway Inhibition
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DOI: 10.3390/cancers14246068
Abstract: Simple Summary Although the initial clinical response of ovarian cancer patients to first-line platinum-based chemotherapy is often excellent, most patients relapse and develop resistance to treatment. However, the mechanism underlying resistance is unclear. DNA repair… read more here.
Keywords: xrcc4; platinum resistance; ovarian cancer; cancer ... See more keywords
Predicting Prognosis and Platinum Resistance in Ovarian Cancer: Role of Immunohistochemistry Biomarkers
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24031973
Abstract: Ovarian cancer is a lethal reproductive tumour affecting women worldwide. The advancement in presentation and occurrence of chemoresistance are the key factors for poor survival among ovarian cancer women. Surgical debulking was the mainstay of… read more here.
Keywords: platinum resistance; ovarian cancer; cancer; immunohistochemistry biomarkers ... See more keywords