Involvement of intestinal efflux and metabolic instability in the pharmacokinetics of platycodin D in rats.
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DOI: 10.1016/j.dmpk.2017.05.005
Abstract: We aimed to investigate the underlying mechanisms for low bioavailability of Platycodin D (PD) in rats. The bioavailability of PD was 1.89% with different half-lives depending on the administration route (2.14 ± 0.18 h for intravenous injection vs… read more here.
Keywords: administration; platycodin rats; upper ileum; involvement intestinal ... See more keywords