Plau/Plaur double-deficiency did not worsen lesion severity or vascular integrity after traumatic brain injury
Sign Up to like & getrecommendations! Published in 2020 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2020.134935
Abstract: Binding of urokinase-type plasminogen activator receptor (uPAR) to its ligand uPA or to its plasma membrane partner, platelet-derived growth factor receptor β (PDGFRβ), promotes neuroprotection, cell proliferation, and angiogenesis. Following injury, single deficiency in uPA… read more here.
Keywords: double deficiency; plaur; tbi; injury ... See more keywords
Comprehensive analysis of the importance of PLAUR in the progression and immune microenvironment of renal clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0269595
Abstract: Clear cell renal cell carcinoma (ccRCC) is a common type of kidney cancer with a high mortality rate, and the discovery of new therapeutic markers is essential to improve patient survival. The plasminogen activator urokinase… read more here.
Keywords: ccrcc; progression; expression; clear cell ... See more keywords
Identification of PLAUR-related ceRNA and immune prognostic signature for kidney renal clear cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.834524
Abstract: Kidney renal clear cell carcinoma (KIRC) represents one of the most fatal cancers, usually showing malignant progression and a high tumor recurrence rate. The urokinase-type plasminogen activator receptor (PLAUR) plays a critical role in the… read more here.
Keywords: cell carcinoma; signature; kidney renal; clear cell ... See more keywords
The Association of PLAUR Genotype and Soluble suPAR Serum Level with COVID-19-Related Lung Damage Severity
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DOI: 10.3390/ijms232416210
Abstract: Uncovering the risk factors for acute respiratory disease coronavirus 2019 (COVID-19) severity may help to provide a valuable tool for early patient stratification and proper treatment implementation, improving the patient outcome and lowering the burden… read more here.
Keywords: serum; covid; severity; plaur ... See more keywords
TCF7L2 promotes anoikis resistance and metastasis of gastric cancer by transcriptionally activating PLAUR
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.69933
Abstract: Gastric cancer (GC) is the most common gastrointestinal malignant tumor, and distant metastasis is a critical factor in the prognosis of patients with GC. Understanding the mechanism of GC metastasis will help improve patient prognosis.… read more here.
Keywords: metastasis; promotes anoikis; resistance metastasis; anoikis resistance ... See more keywords