Conformational dynamics play important roles upon the function of N-acetylglutamate kinase
Sign Up to like & getrecommendations! Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8237-1
Abstract: N-acetylglutamate kinase (NAGK) catalyzes the phosphorylation of N-acetylglutamate. In many bacteria, NAGK catalysis is the rate controlling step in the L-arginine biosynthesis pathway from glutamate to L-arginine and is allosterically inhibited by L-arginine. Many data… read more here.
Keywords: conformational dynamics; acetylglutamate kinase; play important; dynamics play ... See more keywords
Association of GABAA Receptor Gene with Epilepsy Syndromes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-018-1081-7
Abstract: GABA has always been an inviting target in the etiology and treatment of epilepsy. The GABRA1, GABRG2, and GABRD genes provide instructions for making α1, ϒ2, and δ subunits of GABAA receptor protein respectively. GABAA… read more here.
Keywords: gabaa receptor; play important; polymorphism may; gene ... See more keywords
APOBEC-1 cofactors regulate APOBEC3-induced mutations in hepatitis B virus
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Virology"
DOI: 10.1128/jvi.01879-24
Abstract: ABSTRACT APOBEC3 proteins (A3s) play an important role in host innate immunity against viruses and DNA mutations in cancer. A3s-induced mutations in both viral and human DNA genomes vary significantly from non-lethal mutations in viruses… read more here.
Keywords: cancer; mutational activity; induced mutations; mutation ... See more keywords
Circular RNAs in the Central Nervous System
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.629593
Abstract: Circular RNAs (circRNAs) are endogenous single-stranded RNAs characterized by covalently closed loop structures with neither 5′ to 3′ polarity nor poly(A) tails. They are generated most commonly from back-splicing of protein-coding exons. CircRNAs have a… read more here.
Keywords: circular rnas; play important; rnas central; nervous system ... See more keywords
Dynamic Role of Exosome microRNAs in Cancer Cell Signaling and Their Emerging Role as Noninvasive Biomarkers
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DOI: 10.3390/biology12050710
Abstract: Simple Summary Exosomes are vesicles that vary between 40 and 150 nm in diameter and are secreted by cells. These carry miRNAs that have various roles in intercellular signaling. They have different biological functions and… read more here.
Keywords: cell; important role; play important; cancer ... See more keywords