ERG1 plays an essential role in rat cardiomyocyte fate decision by mediating AKT signaling
Sign Up to like & getrecommendations! Published in 2021 at "STEM CELLS"
DOI: 10.1002/stem.3328
Abstract: ERG1, a potassium ion channel, is essential for cardiac action potential repolarization phase. However, the role of ERG1 for normal development of the heart is poorly understood. Using the rat embryonic stem cells (rESCs) model,… read more here.
Keywords: erg1 plays; essential role; plays essential; role ... See more keywords
Phosphatidylserine synthase plays an essential role in glia and affects development, as well as the maintenance of neuronal function
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DOI: 10.1016/j.isci.2021.102899
Abstract: Summary Phosphatidylserine (PS) is an integral component of eukaryotic cell membranes and organelles. The Drosophila genome contains a single PS synthase (PSS)-encoding gene (Pss) homologous to mammalian PSSs. Flies with Pss loss-of-function alleles show a… read more here.
Keywords: synthase plays; synthase; plays essential; function ... See more keywords
The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-23654-3
Abstract: Lysosomes are involved in nutrient sensing via the mechanistic target of rapamycin complex 1 (mTORC1). mTORC1 is tethered to lysosomes by the Ragulator complex, a heteropentamer in which Lamtor1 wraps around Lamtor2–5. Although the Ragulator… read more here.
Keywords: myosin; lysosomal ragulator; ragulator; complex plays ... See more keywords