The establishment of appropriate methods for egg-activation by human PLCZ1 RNA injection into human oocyte.
Sign Up to like & getrecommendations! Published in 2017 at "Cell calcium"
DOI: 10.1016/j.ceca.2017.03.002
Abstract: Phospholipase C-zeta (PLCZ1), a strong candidate of egg-activating sperm factor, can induce Ca2+ oscillations and cause egg activation. For the application of PLCZ1 to clinical use, we examined the pattern of Ca2+ responses and developmental… read more here.
Keywords: human plcz1; rna injection; egg; plcz1 ... See more keywords
Fertilization failure after human ICSI and the clinical potential of PLCZ1.
Sign Up to like & getrecommendations! Published in 2022 at "Reproduction"
DOI: 10.1530/rep-21-0387
Abstract: Two decades have passed since the discovery of phospholipase C zeta (PLCZ1) as the sperm oocyte activating factor. At present, there is a general consensus that PLCZ1 is responsible for triggering the calcium (Ca2+) oscillations… read more here.
Keywords: fertilization failure; plcz1; icsi; failure human ... See more keywords