Pegylated liposomal doxorubicin (PLD) in daily practice-A single center experience of treatment with PLD in patients with comorbidities and older patients with metastatic breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer medicine"
DOI: 10.1002/cam4.6041
Abstract: PURPOSE Real-world data about pegylated liposomal doxorubicin (PLD) in patients with metastatic breast cancer (MBC) are limited. We have aimed to highlight the role of PLD in daily practice focusing on older patients and patients… read more here.
Keywords: older patients; breast cancer; metastatic breast; pld ... See more keywords
Role of PLD−PKCζ signaling axis in p47phox phosphorylation for activation of NADPH oxidase by angiotensin II in pulmonary artery smooth muscle cells
Sign Up to like & getrecommendations! Published in 2019 at "Cell Biology International"
DOI: 10.1002/cbin.11145
Abstract: We sought to determine the mechanism by which angiotensin II (ANGII) stimulates NADPH oxidase‐mediated superoxide (O2.−) production in bovine pulmonary artery smooth muscle cells (BPASMCs). ANGII‐induced increase in phospholipase D (PLD) and NADPH oxidase activities… read more here.
Keywords: oxidase; pkc; pld; angii induced ... See more keywords
Separating spin compartments in arterial spin labeling using delays alternating with nutation for tailored excitation (DANTE) pulse: A validation study using T2 -relaxometry and application to arterial cerebral blood volume imaging.
Sign Up to like & getrecommendations! Published in 2021 at "Magnetic resonance in medicine"
DOI: 10.1002/mrm.29052
Abstract: PURPOSE To clarify the type of spin compartment in arterial spin labeling (ASL) that is eliminated by delays alternating with nutation for tailored excitation (DANTE) pulse using T2 -relaxometry, and to demonstrate the feasibility of… read more here.
Keywords: cbva; dante; arterial spin; pld ... See more keywords
FUS oncofusion protein condensates recruit mSWI/SNF chromatin remodeler via heterotypic interactions between prion‐like domains
Sign Up to like & getrecommendations! Published in 2021 at "Protein Science"
DOI: 10.1002/pro.4127
Abstract: Fusion transcription factors generated by genomic translocations are common drivers of several types of cancers including sarcomas and leukemias. Oncofusions of the FET (FUS, EWSR1, and TAF15) family proteins result from the fusion of the… read more here.
Keywords: protein; chromatin; prion like; pld ... See more keywords
Cardiac safety profile of patients receiving high cumulative doses of pegylated-liposomal doxorubicin: use of left ventricular ejection fraction is of unproven value
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3420-8
Abstract: PurposeOne of the great conundrums for both oncologists and cardiologists is how to best monitor the potential and actual cardiotoxicity of doxorubicin. Pegylated-liposomal doxorubicin (PLD) has a safer cardiotoxicity profile than bolus administration of doxorubicin.… read more here.
Keywords: doxorubicin induced; pegylated liposomal; pld; patients receiving ... See more keywords
Pegylated liposomal doxorubicin-induced renal toxicity in retroperitoneal liposarcoma: a case report and literature review
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-020-04203-z
Abstract: Doxorubicin is one of the most active drugs for sarcoma. Pegylated liposomal doxorubicin (PLD) is a unique formulation of doxorubicin, which carries a more favorable toxicity profile in comparison with free doxorubicin. The main toxicity… read more here.
Keywords: liposomal doxorubicin; pld; case; toxicity ... See more keywords
Aspergillus fumigatus phospholipase D may enhance reactive oxygen species production by accumulation of histone deacetylase 6.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.09.157
Abstract: Aspergillus fumigatus, an airborne pathogen, causes many diseases, including aspergilloma, invasive aspergillosis, and allergic bronchopulmonary aspergillosis. Phospholipase D (PLD) is an important virulence factor for A. fumigatus infection, but the manner by which PLD contributes to… read more here.
Keywords: reactive oxygen; aspergillus fumigatus; production; oxygen species ... See more keywords
Immobilization of phospholipase D on macroporous SiO2/cationic polymer nano-composited support for the highly efficient synthesis of phosphatidylserine.
Sign Up to like & getrecommendations! Published in 2020 at "Enzyme and microbial technology"
DOI: 10.1016/j.enzmictec.2020.109696
Abstract: Novel nano-composites were prepared by coating epoxy resin-based cationic polymer in nano-thickness via in-situ curing on the nano-wall of macroporous SiO2 with pore size of 0.5∼1 μm. By changing the thickness of polymer coating the specific… read more here.
Keywords: immobilized pld; pld; cationic polymer; polymer nano ... See more keywords
The prevention of benign prostatic hyperplasia (bph).
Sign Up to like & getrecommendations! Published in 2017 at "Medical hypotheses"
DOI: 10.1016/j.mehy.2016.12.013
Abstract: Barry Marshall and Robin Warren were the first to show that the chronic diseases (gastric ulcer and chronic gastritis) were caused by an infection (Helicobacter pylori). The chronic disease benign prostatic hyperplasia belongs to the… read more here.
Keywords: benign prostatic; pld; smooth muscle; bph ... See more keywords
Microbial phospholipase D: Identification, modification and application
Sign Up to like & getrecommendations! Published in 2020 at "Trends in Food Science and Technology"
DOI: 10.1016/j.tifs.2019.12.020
Abstract: Abstract Background Phospholipids (PLs) are major components of biological membranes in all living organisms and have been widely applied in the food, pharmaceutical and cosmetic industries for their numerous nutritional and bioactive functions. Traditionally, PLs… read more here.
Keywords: phospholipase identification; pld; application; microbial phospholipase ... See more keywords
Imaging and Editing the Phospholipidome.
Sign Up to like & getrecommendations! Published in 2022 at "Accounts of chemical research"
DOI: 10.1021/acs.accounts.2c00510
Abstract: ConspectusMembranes are multifunctional supramolecular assemblies that encapsulate our cells and the organelles within them. Glycerophospholipids are the most abundant component of membranes. They make up the majority of the lipid bilayer and play both structural… read more here.
Keywords: editing phospholipidome; chemistry; impact; phospholipidome imaging ... See more keywords