Influence of Demographic Factors on Clinical Outcomes in Adults With Chronic Idiopathic Constipation Treated With Plecanatide.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and translational gastroenterology"
DOI: 10.14309/ctg.0000000000000598
Abstract: INTRODUCTION Chronic idiopathic constipation (CIC) is a common condition that affects some patient groups more often. Demographic/clinical characteristics can differ in presentation and therapeutic response. The impact of these characteristics on plecanatide efficacy/safety was examined.… read more here.
Keywords: plecanatide; chronic idiopathic; placebo; influence demographic ... See more keywords
In IBS with constipation, plecanatide reduced abdominal pain and increased bowel movements at 12 wk
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Internal Medicine"
DOI: 10.7326/acpjc-2018-169-2-011
Abstract: Question In patients with irritable bowel syndrome with constipation (IBS-C), what are the efficacy and safety of plecanatide? Methods Design 2 identical randomized placebo-controlled trials. ClinicalTrials.gov NCT02387359 and NCT02493452. Allocation Concealed.* Blinding Blinded* (patients, {health… read more here.
Keywords: trial; treatment; abdominal pain; constipation ... See more keywords