Plectin dysfunction in neurons leads to tau accumulation on microtubules affecting neuritogenesis, organelle trafficking, pain sensitivity and memory
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DOI: 10.1111/nan.12635
Abstract: Plectin, a universally expressed multi‐functional cytolinker protein, is crucial for intermediate filament networking, including crosstalk with actomyosin and microtubules. In addition to its involvement in a number of diseases affecting skin, skeletal muscle, heart, and… read more here.
Keywords: plectin dysfunction; tau accumulation; leads tau; plectin ... See more keywords