Pleiotropic effect of fibrates on senescence and autophagy in osteoarthritis
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.07.018
Abstract: For a long time, research on osteoarthritis (OA) has mainly focused fibrates decrease cartilage damage and reduce both local (synovial) and on alterations and treatment of cartilage morphological features, even though it is now widely… read more here.
Keywords: pleiotropic effect; effect fibrates; fibrates senescence; osteoarthritis ... See more keywords
Verbal memory improvement in first-episode psychosis APOE-ε4 carriers: a pleiotropic effect?
Sign Up to like & getrecommendations! Published in 2017 at "Neuropsychiatric Disease and Treatment"
DOI: 10.2147/ndt.s150488
Abstract: Background Verbal memory impairment is a core feature in schizophrenia even at early stages of the disease, but its etiopathogenesis is not fully understood. The APOE-ε4 is the main genetic risk factor for late-onset Alzheimer’s… read more here.
Keywords: pleiotropic effect; apoe carriers; memory; verbal memory ... See more keywords
Pleiotropic Effect of IL-6 Produced by B-Lymphocytes During Early Phases of Adaptive Immune Responses Against TB Infection
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.750068
Abstract: The role of B cells migrating to the lung and forming follicles during tuberculosis (TB) inflammation is still the subject of debate. In addition to their antibody production and antigen-presenting functions, B cells secrete different… read more here.
Keywords: pleiotropic effect; effect produced; infection; cell ... See more keywords