Pleiotropic effects of GLP-1RAs on peripheral artery disease: Is there any hope?
Sign Up to like & getrecommendations! Published in 2023 at "Diabetes/metabolism research and reviews"
DOI: 10.1002/dmrr.3627
Abstract: NA This article is protected by copyright. All rights reserved. read more here.
Keywords: effects glp; artery disease; peripheral artery; pleiotropic effects ... See more keywords
Stress-induced evolution of herbicide resistance and related pleiotropic effects.
Sign Up to like & getrecommendations! Published in 2018 at "Pest management science"
DOI: 10.1002/ps.5043
Abstract: Herbicide-resistant weeds, especially those with resistance to multiple herbicides, represent a growing worldwide threat to agriculture and food security. Natural selection for resistant genotypes may act on standing genetic variation, or on a genetic and… read more here.
Keywords: herbicide resistance; herbicide; pleiotropic effects; stress induced ... See more keywords
Within- and between-individual (co)variance partitioning reveals limited pleiotropic effects of testosterone on immune function, sexual signaling, and parental investment
Sign Up to like & getrecommendations! Published in 2017 at "Behavioral Ecology and Sociobiology"
DOI: 10.1007/s00265-017-2308-2
Abstract: How and why individuals differ from each other is a central question in behavioral and evolutionary ecology, because selection particularly acts on this among-individual variation. It is therefore important to accurately partition phenotypic variances into… read more here.
Keywords: ecology; pleiotropic effects; sexual signaling; within individual ... See more keywords
The advantages of drug treatment with statins in patients with SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2021 at "Wiener Klinische Wochenschrift"
DOI: 10.1007/s00508-021-01845-8
Abstract: On 11 March 2020 the World Health Organization (WHO) declared a status of global pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019, COVID-19). The pandemic is currently underway,… read more here.
Keywords: advantages drug; drug treatment; treatment; infection ... See more keywords
Pleiotropic Effects of DDT Resistance on Male Size and Behaviour
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DOI: 10.1007/s10519-017-9850-6
Abstract: Understanding the evolution and spread of insecticide resistance requires knowing the relative fitness of resistant organisms. In the absence of insecticides, resistance is predicted to be costly. The Drosophila melanogaster DDT resistance allele (DDT-R) is… read more here.
Keywords: ddt resistance; pleiotropic effects; effects ddt; resistance ... See more keywords
Pleiotropic effects of heparins: does anticoagulant treatment increase survival in cancer patients?
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-018-1835-2
Abstract: The association between venous thromboembolism (VTE) and cancer has been recognized for more than 100 years. Numerous studies have been performed to investigate strategies to decrease VTE incidence and to establish whether treating VTE impacts cancer… read more here.
Keywords: effects heparins; treatment; pleiotropic effects; cancer ... See more keywords
Identification of genetic variants influencing methylation in brain with pleiotropic effects on psychiatric disorders
Sign Up to like & getrecommendations! Published in 2022 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2021.110454
Abstract: Psychiatric disorders affect 29% of the global population at least once in the lifespan, and genetic studies have proved a shared genetic basis among them, although the underlying molecular mechanisms remain largely unknown. DNA methylation… read more here.
Keywords: methylation; psychiatric disorders; genetic variants; pleiotropic effects ... See more keywords
Pleiotropic effects of hemagglutinin amino acid substitutions of influenza A(H1N1)pdm09 virus escape mutants.
Sign Up to like & getrecommendations! Published in 2018 at "Virus research"
DOI: 10.1016/j.virusres.2018.05.002
Abstract: In the present study we assessed pleiotropic characteristics of the antibody-selected mutations. We investigated pH optimum of fusion, temperatures of HA heat inactivation, in vivo and in vitro replication kinetics, and connectivity with panel of… read more here.
Keywords: amino acid; pleiotropic effects; escape mutants; acid substitutions ... See more keywords
Pleiotropic Benefits of Statins in Cardiovascular Diseases.
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DOI: 10.1055/a-1873-1978
Abstract: In 1976, Japanese microbiologist Akira Endo discovered the first statin as a product of the fungus Penicillium citrinum that inhibited the activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Their primary mode of action is to lower… read more here.
Keywords: pleiotropic benefits; statins cardiovascular; cardiovascular diseases; benefits statins ... See more keywords
Diet-mediated metaorganismal relay biotransformation: health effects and pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2021.2004993
Abstract: In recent years, the concept of metaorganism expands our insight into how diet-microbe-host interactions contribute to human health and diseases. We realized that many biological metabolic processes in the host can be summarized into metaorganismal… read more here.
Keywords: pleiotropic effects; metaorganismal relay; diet mediated; effects metabolites ... See more keywords
Unsweetening the Heart: Possible Pleiotropic Effects of SGLT2 Inhibitors on Cardio and Cerebrovascular Alterations in Resistant Hypertensive Subjects
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Hypertension"
DOI: 10.1093/ajh/hpx204
Abstract: Resistant hypertension (RH) is a multifactorial disease associated with several target organ damage, such as microalbuminuria, left ventricular hypertrophy, and arterial stiffness. These subjects have high cardiovascular complications, especially when associated with diabetes condition. Sodium… read more here.
Keywords: heart; sglt inhibitors; pleiotropic effects; heart possible ... See more keywords