PLEKHA5, PLEKHA6, and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis
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DOI: 10.1091/mbc.e21-07-0355
Abstract: Copper homeostasis is crucial for cellular physiology and development, and its dysregulation leads to disease. The Menkes ATPase ATP7A plays a key role in copper efflux, by trafficking from the Golgi to the plasma membrane… read more here.
Keywords: atp7a cell; cell periphery; plekha5 plekha6; copper ... See more keywords