Articles with "plekhf1" as a keyword



PLEKHF1 Induces Mitochondrial Dysfunction to Inhibit Osteosarcoma Growth and Metastasis

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Published in 2025 at "IUBMB Life"

DOI: 10.1002/iub.70048

Abstract: Osteosarcoma (OS) is an uncommon malignancy with stagnant survival rates over the past four decades and early‐stage metastasis, predominantly affecting children and adolescents. This study identified significant metabolic differences between metastatic and non‐metastatic OS samples… read more here.

Keywords: mitochondrial dysfunction; plekhf1; growth metastasis;