Atypical fibroxanthoma and pleomorphic dermal sarcoma: Is superficial infiltration in subcutaneous tissue acceptable in AFX?
Sign Up to like & getrecommendations! Published in 2022 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2022.151915
Abstract: BACKGROUND Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) are rare cutaneous neoplasms forming a spectrum. Case reports with recurrences and metastasis have been published despite the current view that AFX is benign. The aim… read more here.
Keywords: infiltration subcutaneous; pleomorphic dermal; pds; afx ... See more keywords
Integrative Analysis of Pleomorphic Dermal Sarcomas Reveals Fibroblastic Differentiation and Susceptibility to Immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-20-1899
Abstract: Purpose: Pleomorphic dermal sarcoma (PDS) is a rare malignant cutaneous tumor with an unknown cell of origin. Locally defined tumors can be treated by curative excisions, whereas advanced stages of the disease are difficult to… read more here.
Keywords: fibroblastic differentiation; susceptibility immunotherapy; pleomorphic dermal; analysis ... See more keywords
Multifocal pleomorphic dermal sarcoma and the role of inflammation and immunosuppression in a lung transplant patient: a case report
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Case Reports"
DOI: 10.1186/s13256-019-2093-9
Abstract: BackgroundPleomorphic dermal sarcoma is the cutaneous variant of undifferentiated pleomorphic sarcoma. It is a rare malignancy of unclear histogenesis; it is a diagnosis of exclusion that requires extensive use of immunohistochemistry to rule out other… read more here.
Keywords: sarcoma; dermal sarcoma; multifocal pleomorphic; pleomorphic dermal ... See more keywords
Could anti-PD-1 be a therapeutic alternative for metastatic pleomorphic dermal sarcoma?
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Dermatology"
DOI: 10.1684/ejd.2019.3656
Abstract: EJD, vol. 29, n◦ 6, November-December 2019 Patients 1 and 3 reported here), though primary or secondary generalization (as found in Patient 3) can be observed [4]. In Patient 2, radiotherapy was probably not a… read more here.
Keywords: could anti; pleomorphic dermal; alternative metastatic; metastatic pleomorphic ... See more keywords
Immune checkpoint inhibitors for unresectable or metastatic pleomorphic dermal sarcomas
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.975342
Abstract: Pleomorphic dermal sarcomas (PDS) are rare neoplasms of the skin that occur in UV-exposed sites in the elderly, but represent the most common cutaneous sarcomas. Although the majority of PDS can be surgically removed, local… read more here.
Keywords: immune checkpoint; dermal sarcomas; pleomorphic dermal; unresectable metastatic ... See more keywords
A case of pleomorphic dermal sarcoma with perineural invasion treated with Mohs micrographic surgery and adjuvant radiation therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Dermatology online journal"
DOI: 10.5070/d328157063
Abstract: Pleomorphic dermal sarcoma (PDS) was recognized in the 2013 World Health Organization Classification of Tumors of Soft Tissue and Bone as a clinical entity with adverse histopathologic features compared to the more superficial and less… read more here.
Keywords: dermal sarcoma; micrographic surgery; mohs micrographic; pleomorphic dermal ... See more keywords