Articles with "pleomorphic liposarcoma" as a keyword



Pleomorphic liposarcoma: A clinicopathologic study of 20 FNA cases.

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Published in 2022 at "Cancer cytopathology"

DOI: 10.1002/cncy.22580

Abstract: BACKGROUND Pleomorphic liposarcoma (PLPS) is the least common but most aggressive of all forms of liposarcoma (LPS). Its diagnosis relies on the recognition of pleomorphic lipoblasts (PLBs), whose numbers vary considerably. Because few large fine-needle… read more here.

Keywords: clinicopathologic study; pleomorphic liposarcoma; fna biopsy; fna ... See more keywords

Tumor‐targeting Salmonella typhimurium A1‐R arrests a doxorubicin‐resistant PDGFRA‐amplified patient‐derived orthotopic xenograft mouse model of pleomorphic liposarcoma

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Published in 2018 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27183

Abstract: Pleomorphic liposarcoma (PLPS) is a recalcitrant soft‐tissue sarcoma (STS) subtype in need of transformative therapy. We have previously established a patient‐derived orthotopic xenograft (PDOX) model, of PLPS with PDGFRA amplification, using surgical orthotopic implantation. In… read more here.

Keywords: plps pdox; model; typhimurium; pleomorphic liposarcoma ... See more keywords

210 Molecular Silence in High-Grade Sarcomas: Diagnostic Utility of NGS in Three Cases of Pleomorphic Liposarcoma and Undifferentiated Pleomorphic Sarcoma

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Published in 2025 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqaf121.352

Abstract: Pleomorphic liposarcoma (PLS) and undifferentiated pleomorphic sarcoma (UPS) are high-grade sarcomas that remain diagnoses of exclusion, often requiring extensive histologic, immunohistochemical (IHC), and molecular workup. Next-generation sequencing (NGS) is increasingly utilized in soft tissue tumor… read more here.

Keywords: grade sarcomas; high grade; grade; pleomorphic liposarcoma ... See more keywords

Effective apatinib treatment of pleomorphic liposarcoma

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Published in 2017 at "Medicine"

DOI: 10.1097/md.0000000000007771

Abstract: Rationale: Pleomorphic liposarcoma (PLS) is a rare and aggressive malignant tumor, and both radiation and conventional cytotoxic chemotherapy remain controversial for metastatic or unresectable disease. Patient Concerns: We presented an 81-year-old Chinese woman with advanced… read more here.

Keywords: effective apatinib; pleomorphic liposarcoma; apatinib; apatinib treatment ... See more keywords

A Case of Myxoid Pleomorphic Liposarcoma with Rhabdoid Cells: A Diagnostic Pitfall

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Published in 2024 at "International Journal of Surgical Pathology"

DOI: 10.1177/10668969241226695

Abstract: Myxoid pleomorphic liposarcoma (MPLS) is an extremely rare tumor listed in the fifth edition of the WHO classification (2020). Histologically, it mainly comprises a mixture of myxoid and pleomorphic liposarcoma-like components. Genetically, it lacks FUS/EWSR1::DDIT3… read more here.

Keywords: rhabdoid cells; pleomorphic liposarcoma; tumor; myxoid pleomorphic ... See more keywords

Simultaneous pulmonary and inferior vena cava tumor thromboembolism secondary to retroperitoneal pleomorphic liposarcoma.

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Published in 2018 at "Hellenic journal of nuclear medicine"

DOI: 10.1967/s002449910709

Abstract: Retroperitoneal pleomorphic liposarcoma (RPLS) is the least common but the most aggressive subtype of liposarcoma. We herein report a case of tumor embolism (TE) to the inferior vena cava (IVC) and pulmonary arteries in a… read more here.

Keywords: retroperitoneal pleomorphic; vena cava; inferior vena; pleomorphic liposarcoma ... See more keywords

MS-stable/TMB-high pleomorphic liposarcoma successfully treated with pembrolizumab: a case report

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Published in 2025 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2025.1552411

Abstract: Pleomorphic liposarcoma (PLPS) is a rare and aggressive subtype of liposarcoma with limited treatment options. Despite studies on immune checkpoint inhibitors (ICIs) in sarcomas, there have been few reports involving PLPS. Furthermore, the significance of… read more here.

Keywords: tmb high; report; liposarcoma; stable tmb ... See more keywords

Radiation‑induced pleomorphic liposarcoma after hypofractionated radiotherapy following breast‑conserving surgery: A case report and literature review

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Published in 2024 at "Oncology Letters"

DOI: 10.3892/ol.2024.14457

Abstract: Breast cancer is one of the leading causes of cancer globally. Radiotherapy following breast-conserving surgery is the standard treatment of breast cancer. Recently, hypofractionated irradiation comprising 42.56 Gy in 16 fractions was selected as a… read more here.

Keywords: breast; radiation induced; conserving surgery; pleomorphic liposarcoma ... See more keywords
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Pleomorphic Liposarcoma Revisited.

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Published in 2022 at "Orthopedics"

DOI: 10.3928/01477447-20220719-05

Abstract: Pleomorphic liposarcoma (PLPS) is the rarest and more aggressive subtype of liposarcomas, accounting for 10% of all liposarcomas. The diagnosis should be considered after the detection of multivacuolated pleomorphic lipoblasts in biopsy specimens. Wide-margin resection… read more here.

Keywords: liposarcoma revisited; pleomorphic liposarcoma;