CT appearances of pleural infection: analysis of the Second Multi-centre Intra-pleural Sepsis Trial (MIST 2) cohort.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical radiology"
DOI: 10.1016/j.crad.2020.12.017
Abstract: AIM To determine the prevalence of pleural abnormalities and describe the computed tomography (CT) features observed in a well-characterised population of patients with pleural infection. MATERIALS AND METHODS A retrospective study of a subgroup of… read more here.
Keywords: trial; infection; multi centre; pleural infection ... See more keywords
Factors associated with variations in the rate of referrals and microbiology of pleural infection
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Respiratory Medicine"
DOI: 10.1080/17476348.2020.1804874
Abstract: ABSTRACT Objectives Invasive pneumococcal disease is seasonal and associated with influenza, but the same is uncertain for pleural infection. We set out to investigate whether pleural infection referrals similarly correlate with the seasonal variation in… read more here.
Keywords: infection; rate referrals; infection referrals; microbiology ... See more keywords
Use of intrapleural tissue plasminogen activator and deoxyribonuclease in pleural space infections: an update on alternative regimens
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Pulmonary Medicine"
DOI: 10.1097/mcp.0000000000000387
Abstract: Purpose of review Pleural infection remains a common problem with significant associated morbidity and mortality. The current treatment paradigm for pleural infection appears to be shifting as more recent data have suggested that the use… read more here.
Keywords: use intrapleural; intrapleural tissue; space infections; pleural infection ... See more keywords
The role of procalcitonin in the management of pleural infection
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Pulmonary Medicine"
DOI: 10.1097/mcp.0000000000000481
Abstract: Purpose of review Pleural infection is a common problem associated with significant morbidity and mortality. Systemic or pleural fluid markers for reliably identifying pleural infection are limited. Procalcitonin (PCT) is known to be elevated in… read more here.
Keywords: pct; infection; management pleural; pleural infection ... See more keywords
Alteplase Dose Assessment for Pleural infection Therapy (ADAPT) Study‐2: Use of 2.5 mg alteplase as a starting intrapleural dose
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DOI: 10.1111/resp.14261
Abstract: Intrapleural tissue plasminogen activator/deoxyribonuclease (tPA/DNase) therapy is increasingly used in pleural infection. Bleeding risks and costs associated with tPA remain the clinical concerns. Our dose de‐escalation series aims to establish the lowest effective dosing regimen… read more here.
Keywords: alteplase; pleural infection; therapy; study ... See more keywords
Parapneumonic effusions related to Streptococcus pneumoniae: serotype and disease severity trends from 2006 to 2018 in Bristol, UK
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open Respiratory Research"
DOI: 10.1136/bmjresp-2022-001440
Abstract: Rationale Streptococcus pneumoniae epidemiology is changing in response to vaccination and some data suggest that empyema incidence is increasing. However, differences exist between the UK and US studies. We describe trends in the clinical phenotype… read more here.
Keywords: parapneumonic effusions; disease; infection; pleural infection ... See more keywords
P260 The biological effect of tissue plasminogen (t-PA) activator and DNase intrapleural delivery in pleural infection patients
Sign Up to like & getrecommendations! Published in 2018 at "Thorax"
DOI: 10.1136/thorax-2018-212555.416
Abstract: Background Pleural infection (PI) is a major global disease with an increasing incidence. Pleural fluid (PF) drainage is essential for the successful treatment of PI. The MIST 2 study showed that the intrapleural administration of… read more here.
Keywords: dnase; volume; treatment; mcp pathway ... See more keywords
Intrapleural Fibrinolytics and Deoxyribonuclease for Treatment of Indwelling Pleural Catheter-Related Pleural Infection: A Multi-Center Observational Study
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DOI: 10.1159/000514643
Abstract: Background: Indwelling pleural catheters (IPC) are increasingly used for management of recurrent (especially malignant) effusions. Pleural infection associated with IPC use remains a concern. Intrapleural therapy with tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) significantly… read more here.
Keywords: related pleural; infection; tpa dnase; ipc related ... See more keywords
Corticosteroids for Pleural Infection: Should We STOPPE Studying?
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DOI: 10.1164/rccm.202201-0057ed
Abstract: Pleural infection is a challenging condition to manage, and, unlike other infectious diseases, outcomes have improved little over the past decade (1). Pleural infection results in extended hospital stays, a mortality rate of 15%, and… read more here.
Keywords: parapneumonic effusions; infection; pleural infection; trial ... See more keywords
The Biological Role of Pleural Fluid PAI-1 and Sonographic Septations in Pleural Infection: Analysis of a Prospectively Collected Clinical Outcome Study.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of respiratory and critical care medicine"
DOI: 10.1164/rccm.202206-1084oc
Abstract: RATIONALE Sonographic septations are assumed to be important clinical predictors of outcome in pleural infection but the evidence for this is sparse. The inflammatory and fibrinolysis-associated intrapleural pathway(s) leading to septation formation have not been… read more here.
Keywords: pai; infection; septation; pleural infection ... See more keywords
ERS/ESTS statement on the management of pleural infection in adults
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DOI: 10.1183/13993003.01062-2022
Abstract: Pleural infection is a common condition encountered by respiratory physicians and thoracic surgeons alike. The European Respiratory Society (ERS) and European Society of Thoracic Surgeons (ESTS) established a multidisciplinary collaboration of clinicians with expertise in… read more here.
Keywords: infection; pleural infection; ests statement; ers ests ... See more keywords