Update on Novel Targeted Therapy for Pleural Organization and Fibrosis
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DOI: 10.3390/ijms23031587
Abstract: Pleural injury and subsequent loculation is characterized by acute injury, sustained inflammation and, when severe, pathologic tissue reorganization. While fibrin deposition is a normal part of the injury response, disordered fibrin turnover can promote pleural… read more here.
Keywords: update novel; pleural mesothelial; injury; mesothelial cells ... See more keywords
Myo5b Transports Fibronectin-Containing Vesicles and Facilitates FN1 Secretion from Human Pleural Mesothelial Cells
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DOI: 10.3390/ijms23094823
Abstract: Pleural mesothelial cells (PMCs) play a central role in the progression of pleural fibrosis. As pleural injury progresses to fibrosis, PMCs transition to mesenchymal myofibroblast via mesothelial mesenchymal transition (MesoMT), and produce extracellular matrix (ECM)… read more here.
Keywords: pleural mesothelial; fn1; mesothelial cells; fn1 secretion ... See more keywords