A Concise Synthesis of Pleurotin Enabled by a Nontraditional C-H Epimerization.
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DOI: 10.1021/jacs.2c06504
Abstract: An 8-step synthesis of a known pentacyclic intermediate toward the natural product pleurotin (1) is described. Pleurotin and related benzoquinone natural products are of great interest for their powerful anticancer and antibiotic activities. The route… read more here.
Keywords: synthesis pleurotin; epimerization; pleurotin enabled; synthesis ... See more keywords