Bioactive polypeptide hydrogels modified with RGD and N-cadherin mimetic peptide promote chondrogenic differentiation of bone marrow mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2020 at "Science China Chemistry"
DOI: 10.1007/s11426-020-9772-0
Abstract: Cell-material and cell-cell interactions represent two crucial aspects of the regulation of cell behavior. In the present study, poly (L-glutamic acid) (PLG) hydrogels were prepared by catalyst-free click crosslinking via a strain-promoted azide-alkyne cycloaddition (SPAAC)… read more here.
Keywords: plg; marrow mesenchymal; mimetic peptide; cadherin mimetic ... See more keywords
Poly(l-glutamic acid)-cisplatin nanoformulations with detachable PEGylation for prolonged circulation half-life and enhanced cell internalization
Sign Up to like & getrecommendations! Published in 2021 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.01.034
Abstract: PEGylation has been widely applied to prolong the circulation times of nanomedicines via the steric shielding effect, which consequently improves the intratumoral accumulation. However, cell uptake of PEGylated nanoformulations is always blocked by the steric… read more here.
Keywords: plg; circulation; enhanced cell; phe ... See more keywords
Rethinking the accuracy of 75g glucose used in the oral glucose tolerance test in the diagnosis and management of diabetes.
Sign Up to like & getrecommendations! Published in 2017 at "Primary care diabetes"
DOI: 10.1016/j.pcd.2017.06.003
Abstract: AIMS We investigated the specificity of the 75g oral glucose tolerance test (OGTT) and the clinical usefulness of the 2h post loading glucose (2h PLG) value in the clinical care of diabetes patients. METHODS The… read more here.
Keywords: plg; tolerance test; management diabetes; glucose tolerance ... See more keywords
Efficient synthesis of amino acid polymers for protein stabilization.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm00484j
Abstract: Proteins are fragile such that even freezing, drying and dehydration may induce their denaturation, aggregation, and activity loss. To protect proteins from these kinds of damage, we prepared two types of amino acid polymers, poly-(l-glutamate)-r-poly-(l-lysine)… read more here.
Keywords: protein stabilization; acid polymers; plg; amino acid ... See more keywords
Severe dysplasminogenemia due to homozygous PLG Ala620Thr variant in a Korean woman without a history of venous thromboembolism
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029013
Abstract: Abstract Rationale: Plasminogen plays an important role in fibrinolysis and is encoded by the PLG gene. The missense variant PLG Ala620Thr is the major cause of dysplasminogenemia in East Asian countries, including Korea. Although dysplasminogenemia… read more here.
Keywords: homozygous plg; plg; plg ala620thr; ala620thr variant ... See more keywords
Fibrinogen Activates the Capture of Human Plasminogen by Staphylococcal Fibronectin-Binding Proteins
Sign Up to like & getrecommendations! Published in 2017 at "mBio"
DOI: 10.1128/mbio.01067-17
Abstract: ABSTRACT Invasive bacterial pathogens can capture host plasminogen (Plg) and allow it to form plasmin. This process is of medical importance as surface-bound plasmin promotes bacterial spread by cleaving tissue components and favors immune evasion… read more here.
Keywords: mechanism; binding proteins; fibronectin binding; surface ... See more keywords
Derived from poplar leaves graphene-modified silicone rubber composites
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thermoplastic Composite Materials"
DOI: 10.1177/0892705719833119
Abstract: Poplar leaves graphene (PLG) was synthesized from the poplar leaves. Modified poplar leaves graphene (M-PLG) was obtained by graphene treated with silane coupling agent γ-aminopropyltriethoxysilane (KH550). The M-PLG-modified silicone rubber (methyl ethylene silicon rubber [MVQ])… read more here.
Keywords: poplar leaves; leaves graphene; plg; mvq ... See more keywords
Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0180981
Abstract: Plasminogen (Plg) is a precursor of plasmin that degrades fibrin. A race-specific A620T mutation in Plg, also known as Plg-Tochigi, originally identified in a patient with recurrent venous thromboembolism, causes dysplasminogenemia with reduced plasmin activity.… read more here.
Keywords: type mice; plg; mice; wild type ... See more keywords
Performance verification of the new fully automated Aquios flow cytometer PanLeucogate (PLG) platform for CD4-T-lymphocyte enumeration in South Africa
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0187456
Abstract: Background The National Health Laboratory Service (NHLS) offers wide-scale CD4 testing through a network of laboratories in South Africa. A new “load and go” cytometer (Aquios CL, Beckman Coulter), developed with a PLG protocol, was… read more here.
Keywords: south africa; reproducibility; platform; plg ... See more keywords
Plasminogen Binding and Activation at the Mesothelial Cell Surface Promotes Invasion through a Collagen Matrix
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23115984
Abstract: Plasminogen (Plg) activation to the serine protease plasmin (Pla) plays a key role in regulating wound healing and fibrotic responses, particularly when bound to cell surface receptors. Our previous work suggested that mesothelial cells bind… read more here.
Keywords: cell; cell surface; plg; mesothelial cell ... See more keywords
Preparation and Characterization of PLG Microparticles by the Multiple Emulsion Method for the Sustained Release of Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Micromachines"
DOI: 10.3390/mi13101761
Abstract: Rapid release and diminished stability are two of the limitations associated with the growth factors that are essentially used in dental applications. These growth factors are employed to enhance the quality and quantity of tissue… read more here.
Keywords: growth; plg; plg microparticles; encapsulation ... See more keywords