Plasmin and plasminogen prevent sepsis severity by reducing neutrophil extracellular traps and systemic inflammation.
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DOI: 10.1172/jci.insight.166044
Abstract: Sepsis is a lethal syndrome characterized by systemic inflammation and abnormal coagulation. Despite therapeutic advances, sepsis mortality remains substantially high. Herein, we investigated the role of the plasminogen/plasmin (Plg/Pla) system during sepsis. Plasma levels of… read more here.
Keywords: sepsis; plg pla; neutrophil extracellular; sepsis severity ... See more keywords