PGS Scaffolds Promote the In Vivo Survival and Directional Differentiation of Bone Marrow Mesenchymal Stem Cells Restoring the Morphology and Function of Wounded Rat Uterus.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801455
Abstract: Intrauterine adhesion (IUA) causing infertility and recurrent miscarriage of reproductive female mammals usually results from endometrium injury. Nevertheless, there is no efficient therapeutic method to avoid IUA. Bone marrow derived mesenchymal stem cells (BMSCs) are… read more here.
Keywords: collagen; pgs; pgs bmscs; bmscs ... See more keywords
PLGA's Plight and the Role of Stealth Surface Modification Strategies in Its Use for Intravenous Particulate Drug Delivery
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202101536
Abstract: Numerous human disorders can benefit from targeted, intravenous (IV) drug delivery. Polymeric nanoparticles have been designed to undergo systemic circulation and deliver their therapeutic cargo to target sites in a controlled manner. Poly(lactic‐co‐glycolic) acid (PLGA)… read more here.
Keywords: surface; plga; stealth; drug delivery ... See more keywords
Nuclear factor-kappa B (NF-κB) decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid (PLGA) nanospheres promote periodontal tissue healing after tooth replantation in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of periodontology"
DOI: 10.1002/jper.21-0134
Abstract: BACKGROUND Excessive inflammation in the periodontal tissue after tooth replantation can lead to inflammatory root resorption and interrupt periodontal tissue regeneration. We tested the hypothesis that NF-κB decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres (NF-PLGA) inhibit… read more here.
Keywords: tooth replantation; plga; periodontal tissue; factor ... See more keywords
Comparative study of NMP‐preloaded and dip‐loaded membranes for guided bone regeneration of rabbit cranial defects
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1926
Abstract: Guided bone regeneration (GBR) has been utilized for several decades for the healing of cranio‐maxillofacial bone defects and, particularly in the dental field, by creating space with a barrier membrane to exclude soft tissue and… read more here.
Keywords: bone regeneration; guided bone; regeneration; bone ... See more keywords
Peptide nanostructures on nanofibers for peripheral nerve regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2860
Abstract: Self‐assembled peptide nanofibrous scaffolds with designer sequences, similar to neurite growth promoting molecules enhance the differentiation of neural stem cells. However, self‐assembled peptide nanofibrous scaffolds lack the required mechanical strength to suffice to bridge long… read more here.
Keywords: peptide; peripheral nerve; regeneration; peptide nanostructures ... See more keywords
Superior Synaptogenic Effect of Electrospun PLGA-PEG Nanofibers Versus PLGA Nanofibers on Human Neural SH-SY5Y Cells in a Three-Dimensional Culture System
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01596-7
Abstract: Synapses are touted as the main structural and functional components of neural cells within in the nervous system, providing tissue connectivity and integration via the formation of perineuronal nets. In the present study, we evaluated… read more here.
Keywords: peg nanofibers; electrospun plga; plga plga; plga peg ... See more keywords
D-Optimal Optimization and Data-Analysis Comparison Between a DoE Software and Artificial Neural Networks of a Chitosan Coating Process onto PLGA Nanoparticles for Lung and Cervical Cancer Treatment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-018-9345-x
Abstract: PurposeA common approach to “Quality-by-Design” is to employ quality software(s) to characterize the impacts of input parameters on output-critical quality attributes. In this study, paclitaxel (PTX), a common chemotherapeutic agent, was loaded into poly-lactic-co-glycolic acid… read more here.
Keywords: plga nanoparticles; coating process; optimization; onto plga ... See more keywords
Preparation of Paclitaxel and Etoposide Co-loaded mPEG-PLGA Nanoparticles: an Investigation with Artificial Neural Network
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-019-09419-y
Abstract: Purpose The main purpose of this study was to develop etoposide (ETP) and paclitaxel (PTX) co-loaded methoxy poly(ethylene glycol)-poly(lactic-co-glycolic acid) (mPEG-PLGA) nanoparticles (NPs) with optimized size to achieve co-delivery of ETP and PTX. In addition,… read more here.
Keywords: plga nanoparticles; loaded mpeg; plga; mpeg plga ... See more keywords
The PLGA Microspheres Synthesized by a Thermosensitive Hydrogel Emulsifier for Sustained Release of Risperidone
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-021-09544-7
Abstract: Risperidone is an important antipsychotic agent used for treatment of both acute and chronic schizophrenia. The drug has been effective in resolving the disease’s signs while keeping extrapyramidal side effects as low as possible. To… read more here.
Keywords: drug; risperidone; plga; plga microspheres ... See more keywords
Nose-to-brain delivery of lamotrigine-loaded PLGA nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-019-00622-5
Abstract: Direct nose-to-brain delivery of drugs and faster onset of action have made intra-nasal route a much sought-after alternative to conventional routes of drug delivery to the brain. Lamotrigine is used for the treatment and management… read more here.
Keywords: ltg plga; plga nanoparticles; delivery; drug ... See more keywords
Nanofibrous PLGA electrospun scaffolds modified with type I collagen influence hepatocyte function and support viability in vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.02.009
Abstract: A major challenge of maintaining primary hepatocytes in vitro is progressive loss of hepatocyte-specific functions, such as protein synthesis and cytochrome P450 (CYP450) catalytic activity. We developed a three-dimensional (3D) nanofibrous scaffold made from poly(l-lactide-co-glycolide)… read more here.
Keywords: collagen; type collagen; plga; hepatocyte function ... See more keywords