PGS Scaffolds Promote the In Vivo Survival and Directional Differentiation of Bone Marrow Mesenchymal Stem Cells Restoring the Morphology and Function of Wounded Rat Uterus.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201801455
Abstract: Intrauterine adhesion (IUA) causing infertility and recurrent miscarriage of reproductive female mammals usually results from endometrium injury. Nevertheless, there is no efficient therapeutic method to avoid IUA. Bone marrow derived mesenchymal stem cells (BMSCs) are… read more here.
Keywords: collagen; pgs; pgs bmscs; bmscs ... See more keywords
PLGA's Plight and the Role of Stealth Surface Modification Strategies in Its Use for Intravenous Particulate Drug Delivery
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202101536
Abstract: Numerous human disorders can benefit from targeted, intravenous (IV) drug delivery. Polymeric nanoparticles have been designed to undergo systemic circulation and deliver their therapeutic cargo to target sites in a controlled manner. Poly(lactic‐co‐glycolic) acid (PLGA)… read more here.
Keywords: surface; plga; stealth; drug delivery ... See more keywords
Nuclear factor-kappa B (NF-κB) decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid (PLGA) nanospheres promote periodontal tissue healing after tooth replantation in rats.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of periodontology"
DOI: 10.1002/jper.21-0134
Abstract: BACKGROUND Excessive inflammation in the periodontal tissue after tooth replantation can lead to inflammatory root resorption and interrupt periodontal tissue regeneration. We tested the hypothesis that NF-κB decoy oligodeoxynucleotide-loaded poly lactic-co-glycolic acid nanospheres (NF-PLGA) inhibit… read more here.
Keywords: tooth replantation; plga; periodontal tissue; factor ... See more keywords
Enhanced Poly(Lactic‐Co‐Glycolic Acid) Composite for Bone Tissue Repair Applications: A Comprehensive Optimization Approach
Sign Up to like & getrecommendations! Published in 2025 at "Macromolecular Materials and Engineering"
DOI: 10.1002/mame.202500084
Abstract: This study explores Poly(lactic‐co‐glycolic acid) (PLGA)‐based scaffolds modified with 10 wt% polycaprolactone (PCL), polylactic acid (PLA), and polyurethane (PU) to enhance their performance. The composite films were characterized by tensile testing, degradability, water absorption, thermal… read more here.
Keywords: lactic glycolic; plga pla; glycolic acid; plga ... See more keywords
Comparative study of NMP‐preloaded and dip‐loaded membranes for guided bone regeneration of rabbit cranial defects
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.1926
Abstract: Guided bone regeneration (GBR) has been utilized for several decades for the healing of cranio‐maxillofacial bone defects and, particularly in the dental field, by creating space with a barrier membrane to exclude soft tissue and… read more here.
Keywords: bone regeneration; guided bone; regeneration; bone ... See more keywords
Peptide nanostructures on nanofibers for peripheral nerve regeneration
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2860
Abstract: Self‐assembled peptide nanofibrous scaffolds with designer sequences, similar to neurite growth promoting molecules enhance the differentiation of neural stem cells. However, self‐assembled peptide nanofibrous scaffolds lack the required mechanical strength to suffice to bridge long… read more here.
Keywords: peptide; peripheral nerve; regeneration; peptide nanostructures ... See more keywords
Diffusion of curcumin in PLGA-based carriers for drug delivery: a molecular dynamics study
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-024-06023-x
Abstract: The rapid growth and diversification of drug delivery systems have been significantly supported by advancements in micro- and nano-technologies, alongside the adoption of biodegradable polymeric materials like poly(lactic-co-glycolic acid) (PLGA) as microcarriers. These developments aim… read more here.
Keywords: drug delivery; plga; drug; curcumin ... See more keywords
Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles
Sign Up to like & getrecommendations! Published in 2024 at "Pharmaceutical Research"
DOI: 10.1007/s11095-024-03665-7
Abstract: A dissolving microneedle array (dMNA) is a vaccine delivery device with several advantages over conventional needles. By incorporating particulate adjuvants in the form of poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) into the dMNA, the immune response… read more here.
Keywords: dmna; plga; cpg; plga nanoparticles ... See more keywords
Superior Synaptogenic Effect of Electrospun PLGA-PEG Nanofibers Versus PLGA Nanofibers on Human Neural SH-SY5Y Cells in a Three-Dimensional Culture System
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-020-01596-7
Abstract: Synapses are touted as the main structural and functional components of neural cells within in the nervous system, providing tissue connectivity and integration via the formation of perineuronal nets. In the present study, we evaluated… read more here.
Keywords: peg nanofibers; electrospun plga; plga plga; plga peg ... See more keywords
Synthesis of Novel Plant-Derived Encapsulated Radiolabeled Compounds for the Diagnosis of Parkinson’s Disease and the Evaluation of Biological Effects with In Vitro/In Vivo Methods
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Neurobiology"
DOI: 10.1007/s12035-024-04103-w
Abstract: Parkinson’s disease (PD) is a neurodegenerative disorder that affects millions of individuals globally. It is characterized by the loss of dopaminergic neurons in Substantia Nigra pars compacta (SNc) and striatum. Neuroimaging techniques such as single-photon… read more here.
Keywords: spectroscopy; plant derived; plga; radiolabeled compounds ... See more keywords
D-Optimal Optimization and Data-Analysis Comparison Between a DoE Software and Artificial Neural Networks of a Chitosan Coating Process onto PLGA Nanoparticles for Lung and Cervical Cancer Treatment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-018-9345-x
Abstract: PurposeA common approach to “Quality-by-Design” is to employ quality software(s) to characterize the impacts of input parameters on output-critical quality attributes. In this study, paclitaxel (PTX), a common chemotherapeutic agent, was loaded into poly-lactic-co-glycolic acid… read more here.
Keywords: plga nanoparticles; coating process; optimization; onto plga ... See more keywords