A novel antigen of Mycobacterium tuberculosis and MPLA adjuvant co-entrapped into PLGA:DDA hybrid nanoparticles stimulates mucosal and systemic immunity.
Sign Up to like & getrecommendations! Published in 2018 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2018.10.023
Abstract: BACKGROUND Due to initiation of Mycobacterium tuberculosis infection via the mucosal tissue of the respiratory tract, intranasal administration of new tuberculosis vaccines is highly regarded to enhance mucosal immunity. Our outline was evaluation of mucosal… read more here.
Keywords: plga dda; mpla; tuberculosis; mucosal systemic ... See more keywords
Enhancing immunogenicity of novel multistage subunit vaccine of Mycobacterium tuberculosis using PLGA:DDA hybrid nanoparticles and MPLA: Subcutaneous administration
Sign Up to like & getrecommendations! Published in 2019 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2019.33962.8079
Abstract: Objective(s): A new strategy in recent studies is using effective tuberculosis (TB) subunit vaccines combined with appropriate carriers and adjuvants which have shown promising results in preclinical and clinical studies. The aim of the present… read more here.
Keywords: plga dda; tuberculosis; dda; hspx esxs ... See more keywords