Fabricating PLGA microparticles with high loads of the small molecule antioxidant N‐acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26443
Abstract: Reactive oxygen species (ROS), encompassing all oxygen radical or non‐radical oxidizing agents, play key roles in disease progression. Controlled delivery of antioxidants is therapeutically relevant in such oxidant‐stressed environments. Encapsulating small hydrophilic molecules into hydrophobic… read more here.
Keywords: doped particles; plga microparticles; high loads; drug ... See more keywords
Micro‐Flow Imaging as a quantitative tool to assess size and agglomeration of PLGA microparticles
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.04.002
Abstract: Graphical abstract Figure. No caption available. ABSTRACT The purpose of this study was to explore the potential of flow imaging microscopy to measure particle size and agglomeration of poly(lactic‐co‐glycolic acid) (PLGA) microparticles. The particle size… read more here.
Keywords: flow imaging; plga microparticles; size agglomeration; size ... See more keywords
The Acute Immune Responses of the Common Carp Cyprinus carpio to PLGA Microparticles—The Interactions of a Teleost Fish with a Foreign Material
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12020326
Abstract: Poly lactic-co-glycolic acid (PLGA) particles safely and effectively deliver pharmaceutical ingredients, with many applications approved for clinical use in humans. In fishes, PLGA particles are being considered as carriers of therapeutic drugs and vaccine antigens.… read more here.
Keywords: teleost fish; plga microparticles; common carp; plga ... See more keywords
Development of L-Lysine-Loaded PLGA Microparticles as a Controlled Release System for Angiogenesis Enhancement
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020479
Abstract: Vascularization is a highly conserved and considerably complex and precise process that is finely driven by endogenous regulatory processes at the tissue and systemic levels. However, it can reveal itself to be slow and inadequate… read more here.
Keywords: system; development; controlled release; release ... See more keywords