A doxorubicin and vincristine drug release system based on magnetic PLGA microspheres prepared by coaxial electrospray
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Science"
DOI: 10.1007/s10853-019-03575-9
Abstract: In this study, we demonstrated a novel doxorubicin and vincristine-loaded PLGA magnetic microspheres prepared by coaxial electrospray, as a drug delivery system for osteosarcoma treatment. The results showed that microspheres had an minimum mean diameter… read more here.
Keywords: plga microspheres; prepared coaxial; coaxial electrospray; microspheres prepared ... See more keywords
The PLGA Microspheres Synthesized by a Thermosensitive Hydrogel Emulsifier for Sustained Release of Risperidone
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-021-09544-7
Abstract: Risperidone is an important antipsychotic agent used for treatment of both acute and chronic schizophrenia. The drug has been effective in resolving the disease’s signs while keeping extrapyramidal side effects as low as possible. To… read more here.
Keywords: drug; risperidone; plga; plga microspheres ... See more keywords
Exosome-modified PLGA Microspheres for Improved Internalization into Dendritic Cells and Macrophages
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Bioprocess Engineering"
DOI: 10.1007/s12257-020-0008-7
Abstract: Considering the significance of effective antigen presentation for boosting immune responses, it is essential to develop delivery systems for antigen presenting cells (APCs; dendritic cells and macrophages). As a simple and facile way for improving… read more here.
Keywords: plga microspheres; cells macrophages; modified plga; microspheres improved ... See more keywords
TCPP/MgO-loaded PLGA microspheres combining photodynamic antibacterial therapy with PBM-assisted fibroblast activation to treat periodontitis.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01959k
Abstract: Bacteria eradication and subsequent periodontal tissue reconstruction is the primary task for periodontitis treatment. Commonly used antibiotic therapy suffers from antibiotic resistance. Meanwhile, promoting fibroblast activity is crucial for re-establishing a damaged periodontal structure. In… read more here.
Keywords: pbm; fibroblast activation; therapy; plga microspheres ... See more keywords
Influence of drying processes on the structures, morphology and in vitro release profiles of risperidone-loaded PLGA microspheres
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2019.1582723
Abstract: Abstract The purpose of this study was to investigate the influences of drying methods on the risperidone (RIS) release profiles of RIS-loaded PLGA microspheres. These microspheres were fabricated with an O/W emulsion solvent evaporation method.… read more here.
Keywords: plga microspheres; influence; release profiles; loaded plga ... See more keywords
Preparation of uniform-sized GeXIVA[1,2]-loaded PLGA microspheres as long-effective release system with high encapsulation efficiency
Sign Up to like & getrecommendations! Published in 2022 at "Drug Delivery"
DOI: 10.1080/10717544.2022.2089297
Abstract: Abstract The purpose of this study was to prepare GeXIVA[1,2] PLGA microspheres by W/O/W re-emulsification-solvent evaporation technology and to develop sustained-release formulations to meet the clinical treatment needs of chronic neuropathic pain. Through prescription optimization,… read more here.
Keywords: plga microspheres; encapsulation; release; encapsulation efficiency ... See more keywords
Engineered PLGA microspheres for extended-release of naltrexone: in vitro, in vivo, and IVIVR
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2023.2172041
Abstract: Abstract Poly(lactide-co-glycolide) (PLGA)-based formulation is one of the most often used parenteral extended-release forms to deliver various therapeutics. VIVITROL® as a commercialized PLGA microsphere formulation encapsulates naltrexone, a narcotic antagonist for opioid addiction and alcohol… read more here.
Keywords: vivo; plga microspheres; release; extended release ... See more keywords
Bridging the gap between fundamental research and product development of long acting injectable PLGA microspheres
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2022.2105317
Abstract: ABSTRACT Introduction Long-acting Injectable PLGA microspheres have gained more and more interest and attention in the field of life cycle management of pharmaceutical products due to their biocompatibility and biodegradability. So far, a multitude of… read more here.
Keywords: development; plga microspheres; acting injectable; long acting ... See more keywords
Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress
Sign Up to like & getrecommendations! Published in 2020 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2020/8586314
Abstract: There is a high incidence of acute and chronic skin defects caused by various reasons in clinically practice. The repair and functional reconstruction of skin defects have become a major clinical problem, which needs to… read more here.
Keywords: wound healing; plga microspheres; fgf10 plga; fibroblast growth ... See more keywords
Preparation, Characterization and in vitro/in vivo Evaluation of Lovastatin-Loaded PLGA Microspheres by Local Administration for Femoral Head Necrosis
Sign Up to like & getrecommendations! Published in 2021 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s286306
Abstract: Background The present work is an effort to develop a novel locally injection LVTT-loaded PLGA microspheres (LVTT-PLGA-MS) on the treatment of rabbits with femoral head necrosis (FHN). Methods LVTT-loaded PLGA microspheres (LVTT-PLGA MS) were prepared… read more here.
Keywords: femoral head; plga microspheres; head necrosis; loaded plga ... See more keywords
Qualification of Non-Halogenated Organic Solvents Applied to Microsphere Manufacturing Process
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12050425
Abstract: As a non-halogenated dispersed solvent, ethyl acetate has been most commonly used for the manufacturing of poly-d,l-lactide-co-glycolide (PLGA) microspheres. However, ethyl acetate-based microencapsulation processes face several limitations. This study was aimed at proposing ethyl formate… read more here.
Keywords: plga microspheres; ethyl; process; non halogenated ... See more keywords