Ultrastructural and physicochemical characterization of pH receptive chlorhexidine-loaded poly-L-glycolic acid-modified orthodontic adhesive.
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy research and technique"
DOI: 10.1002/jemt.23968
Abstract: This study aims to evaluate the feasibility of chlorhexidine (CHX)-loaded poly-L-glycolic acid (PLGA) nanoparticles as a modifier of a commercial orthodontic adhesive via the assessment of physicochemical, biological, and mechanical properties at tooth-bracket interface. CHX-loaded… read more here.
Keywords: plga nanoparticles; loaded plga; chx loaded; orthodontic adhesive ... See more keywords
RETRACTED: In Vitro Neuroprotective Effect Evaluation of Donepezil‐Loaded PLGA Nanoparticles‐Embedded PVA/PEG Nanofibers on SH‐SY5Y Cells and AP‐APP Plasmid Related Alzheimer Cell Line Model
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular Materials and Engineering"
DOI: 10.1002/mame.202400160
Abstract: Recently developed nanoparticles and nanofibers present new brain‐specific treatment strategies, especially for Alzheimer's disease treatment. In this study, donepezil (DO)‐loaded PLGA nanoparticles (DNP) are embedded in PVA/PEG nanofibers (DNPF) produced by pressurized gyration for sublingual… read more here.
Keywords: alzheimer; pva peg; donepezil loaded; loaded plga ... See more keywords
Efficient Co‐Loading of Paclitaxel and Gefitinib in PLGA Nanoparticles: Use of Design of Experiments (DoE) Approach for Enhanced Efficacy Against MCF‐7/MCF‐7ADR Cells
Sign Up to like & getrecommendations! Published in 2025 at "Polymers for Advanced Technologies"
DOI: 10.1002/pat.70424
Abstract: In this study co‐loading of paclitaxel and gefitinib in PLGA nanoparticles for breast cancer treatment has been explored as a strategy to overcome limitations of using the drug alone. Combination index studies using Chou–Talay method… read more here.
Keywords: plga nanoparticles; loading paclitaxel; paclitaxel gefitinib; gefitinib plga ... See more keywords
Efficacy of Surface-Modified PLGA Nanoparticles as a Function of Cervical Cancer Type
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Research"
DOI: 10.1007/s11095-019-2602-y
Abstract: PurposeHypovascularization of cervical tumors, coupled with intrinsic and acquired drug resistance, has contributed to marginal therapeutic outcomes by hindering chemotherapeutic transport and efficacy. Recently, the heterogeneous penetration and distribution of cell penetrating peptide (CPP, here… read more here.
Keywords: plga nanoparticles; surface modified; cervical cancer; efficacy ... See more keywords
Intradermal Vaccination with PLGA Nanoparticles via Dissolving Microneedles and Classical Injection Needles
Sign Up to like & getrecommendations! Published in 2024 at "Pharmaceutical Research"
DOI: 10.1007/s11095-024-03665-7
Abstract: A dissolving microneedle array (dMNA) is a vaccine delivery device with several advantages over conventional needles. By incorporating particulate adjuvants in the form of poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) into the dMNA, the immune response… read more here.
Keywords: dmna; plga; cpg; plga nanoparticles ... See more keywords
New Insights of Turmeric Extract-Loaded PLGA Nanoparticles: Development, Characterization and In Vitro Evaluation of Antioxidant Activity
Sign Up to like & getrecommendations! Published in 2021 at "Plant Foods for Human Nutrition"
DOI: 10.1007/s11130-021-00929-0
Abstract: Here, we presented new insights of the development of poly(lactic-co-glycolic acid) nanoparticles containing turmeric compounds (turmeric-PLGA-NPs) using emulsion-solvent evaporation method. The nanoparticulate system was characterized by size, zeta potential, morphology, release profile, partition parameter, stability… read more here.
Keywords: antioxidant activity; plga nanoparticles; turmeric extract; plga nps ... See more keywords
D-Optimal Optimization and Data-Analysis Comparison Between a DoE Software and Artificial Neural Networks of a Chitosan Coating Process onto PLGA Nanoparticles for Lung and Cervical Cancer Treatment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-018-9345-x
Abstract: PurposeA common approach to “Quality-by-Design” is to employ quality software(s) to characterize the impacts of input parameters on output-critical quality attributes. In this study, paclitaxel (PTX), a common chemotherapeutic agent, was loaded into poly-lactic-co-glycolic acid… read more here.
Keywords: plga nanoparticles; coating process; optimization; onto plga ... See more keywords
Preparation of Paclitaxel and Etoposide Co-loaded mPEG-PLGA Nanoparticles: an Investigation with Artificial Neural Network
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-019-09419-y
Abstract: Purpose The main purpose of this study was to develop etoposide (ETP) and paclitaxel (PTX) co-loaded methoxy poly(ethylene glycol)-poly(lactic-co-glycolic acid) (mPEG-PLGA) nanoparticles (NPs) with optimized size to achieve co-delivery of ETP and PTX. In addition,… read more here.
Keywords: plga nanoparticles; loaded mpeg; plga; mpeg plga ... See more keywords
Development and Optimization of Alendronate Sodium Loaded PLGA Nanoparticles by Central Composite Design
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular Research"
DOI: 10.1007/s13233-019-7119-z
Abstract: AbstractAlendronate sodium (AS) which supresses the activity of osteoclastic cells and leads to the inhibition of bone resorption, is one of the most clinically preferred drug for the treatment of osteoporosis. The purpose of this… read more here.
Keywords: plga nanoparticles; nanoparticle; sodium; method ... See more keywords
Nose-to-brain delivery of lamotrigine-loaded PLGA nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-019-00622-5
Abstract: Direct nose-to-brain delivery of drugs and faster onset of action have made intra-nasal route a much sought-after alternative to conventional routes of drug delivery to the brain. Lamotrigine is used for the treatment and management… read more here.
Keywords: ltg plga; plga nanoparticles; delivery; drug ... See more keywords
Comparative study of cilnidipine loaded PLGA nanoparticles: process optimization by DoE, physico-chemical characterization and in vivo evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-020-00732-5
Abstract: Cilnidipine (CND) is known to have low oral bioavailability due to its poor aqueous solubility, low dissolution rate, and high gut wall metabolism. In the present study, CND-loaded PLGA nanoparticles (CND-PLGA-NPs) were prepared with two… read more here.
Keywords: cnd plga; plga nanoparticles; cnd; loaded plga ... See more keywords