Ultrastructural and physicochemical characterization of pH receptive chlorhexidine-loaded poly-L-glycolic acid-modified orthodontic adhesive.
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy research and technique"
DOI: 10.1002/jemt.23968
Abstract: This study aims to evaluate the feasibility of chlorhexidine (CHX)-loaded poly-L-glycolic acid (PLGA) nanoparticles as a modifier of a commercial orthodontic adhesive via the assessment of physicochemical, biological, and mechanical properties at tooth-bracket interface. CHX-loaded… read more here.
Keywords: plga nanoparticles; loaded plga; chx loaded; orthodontic adhesive ... See more keywords
Efficacy of Surface-Modified PLGA Nanoparticles as a Function of Cervical Cancer Type
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Research"
DOI: 10.1007/s11095-019-2602-y
Abstract: PurposeHypovascularization of cervical tumors, coupled with intrinsic and acquired drug resistance, has contributed to marginal therapeutic outcomes by hindering chemotherapeutic transport and efficacy. Recently, the heterogeneous penetration and distribution of cell penetrating peptide (CPP, here… read more here.
Keywords: plga nanoparticles; surface modified; cervical cancer; efficacy ... See more keywords
New Insights of Turmeric Extract-Loaded PLGA Nanoparticles: Development, Characterization and In Vitro Evaluation of Antioxidant Activity
Sign Up to like & getrecommendations! Published in 2021 at "Plant Foods for Human Nutrition"
DOI: 10.1007/s11130-021-00929-0
Abstract: Here, we presented new insights of the development of poly(lactic-co-glycolic acid) nanoparticles containing turmeric compounds (turmeric-PLGA-NPs) using emulsion-solvent evaporation method. The nanoparticulate system was characterized by size, zeta potential, morphology, release profile, partition parameter, stability… read more here.
Keywords: antioxidant activity; plga nanoparticles; turmeric extract; plga nps ... See more keywords
D-Optimal Optimization and Data-Analysis Comparison Between a DoE Software and Artificial Neural Networks of a Chitosan Coating Process onto PLGA Nanoparticles for Lung and Cervical Cancer Treatment
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-018-9345-x
Abstract: PurposeA common approach to “Quality-by-Design” is to employ quality software(s) to characterize the impacts of input parameters on output-critical quality attributes. In this study, paclitaxel (PTX), a common chemotherapeutic agent, was loaded into poly-lactic-co-glycolic acid… read more here.
Keywords: plga nanoparticles; coating process; optimization; onto plga ... See more keywords
Preparation of Paclitaxel and Etoposide Co-loaded mPEG-PLGA Nanoparticles: an Investigation with Artificial Neural Network
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-019-09419-y
Abstract: Purpose The main purpose of this study was to develop etoposide (ETP) and paclitaxel (PTX) co-loaded methoxy poly(ethylene glycol)-poly(lactic-co-glycolic acid) (mPEG-PLGA) nanoparticles (NPs) with optimized size to achieve co-delivery of ETP and PTX. In addition,… read more here.
Keywords: plga nanoparticles; loaded mpeg; plga; mpeg plga ... See more keywords
Development and Optimization of Alendronate Sodium Loaded PLGA Nanoparticles by Central Composite Design
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular Research"
DOI: 10.1007/s13233-019-7119-z
Abstract: AbstractAlendronate sodium (AS) which supresses the activity of osteoclastic cells and leads to the inhibition of bone resorption, is one of the most clinically preferred drug for the treatment of osteoporosis. The purpose of this… read more here.
Keywords: plga nanoparticles; nanoparticle; sodium; method ... See more keywords
Nose-to-brain delivery of lamotrigine-loaded PLGA nanoparticles
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-019-00622-5
Abstract: Direct nose-to-brain delivery of drugs and faster onset of action have made intra-nasal route a much sought-after alternative to conventional routes of drug delivery to the brain. Lamotrigine is used for the treatment and management… read more here.
Keywords: ltg plga; plga nanoparticles; delivery; drug ... See more keywords
Comparative study of cilnidipine loaded PLGA nanoparticles: process optimization by DoE, physico-chemical characterization and in vivo evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-020-00732-5
Abstract: Cilnidipine (CND) is known to have low oral bioavailability due to its poor aqueous solubility, low dissolution rate, and high gut wall metabolism. In the present study, CND-loaded PLGA nanoparticles (CND-PLGA-NPs) were prepared with two… read more here.
Keywords: cnd plga; plga nanoparticles; cnd; loaded plga ... See more keywords
Design, synthesis, and antitumor activity of PLGA nanoparticles incorporating a discovered benzimidazole derivative as EZH2 inhibitor.
Sign Up to like & getrecommendations! Published in 2021 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2021.109530
Abstract: PURPOSE Targeting enhancer of zeste homolog 2 (EZH2) can represent a hopeful strategy for oncotherapy. Also, the use of PLGA-based nanoparticles as a novel and rate-controlling carrier system was of our concern. METHODS Benzimidazole derivatives… read more here.
Keywords: plga nanoparticles; activity; ezh2; antitumor activity ... See more keywords
Curcumin encapsulation in functional PLGA nanoparticles: A promising strategy for cancer therapies.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in colloid and interface science"
DOI: 10.1016/j.cis.2021.102582
Abstract: Nanoparticles have emerged as promising drug delivery systems for the treatment of several diseases. Novel cancer therapies have exploited these particles as alternative adjuvant therapies to overcome the traditional limitations of radio and chemotherapy. Curcumin… read more here.
Keywords: cancer; curcumin encapsulation; cancer therapies; plga nanoparticles ... See more keywords
Skin permeability and transdermal delivery route of 30-nm cyclosporin A-loaded nanoparticles using PLGA-PEG-PLGA triblock copolymer
Sign Up to like & getrecommendations! Published in 2020 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2020.124866
Abstract: Abstract The aim of this study was to investigate the skin permeability of a hydrophobic drug when using poly( dl -lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly( dl -lactide-co-glycolide) triblock copolymers (PLGA-PEG-PLGA) as a drug carrier. Two types of PLGA-PEG-PLGA… read more here.
Keywords: plga nanoparticles; drug; plga peg; peg plga ... See more keywords