Using ultrasound and angiogenic markers from a 19-23 week assessment to inform the subsequent diagnosis of preeclampsia.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of obstetrics and gynecology"
DOI: 10.1016/j.ajog.2022.03.007
Abstract: BACKGROUND A definition of preeclampsia (PE) that incorporates assessment of maternal, fetal, and uteroplacental status optimizes identification of pregnancies at risk of complications at term gestational age. This includes 'carrying forward' angiogenic test results from… read more here.
Keywords: week; assessment; morbidity; plgf ... See more keywords
A flibercept regulates retinal inflammation elicited by high glucose via the PlGF/ERK pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.07.021
Abstract: Diabetic retinopathy (DR) is a secondary complication of diabetes. DR can cause irreversible blindness, and its pathogenesis has been considered multifactorial. DR can progress from non-proliferative DR to proliferative DR, characterized by retinal neovascularization. The… read more here.
Keywords: aflibercept anti; retinal inflammation; plgf; flibercept regulates ... See more keywords
Full Functional Knockout of Placental Growth Factor by Knockin with an Inactive Variant Able to Heterodimerize with VEGF-A.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.05.067
Abstract: Placental growth factor (PlGF) is a proangiogenic member of the vascular endothelial growth factor (VEGF) family playing a central role in pathological angiogenesis. PlGF-DE is a PlGF variant unable to bind vascular endothelial growth factor… read more here.
Keywords: plgf; placental growth; growth factor; growth ... See more keywords
Blockade of placental growth factor reduces vaso-occlusive complications in murine models of sickle cell disease.
Sign Up to like & getrecommendations! Published in 2018 at "Experimental hematology"
DOI: 10.1016/j.exphem.2018.01.002
Abstract: Vaso-occlusive crisis (VOC) is the most common and debilitating complication of sickle cell disease (SCD); recurrent episodes cause organ damage and contribute to early mortality. Plasma placental growth factor (PlGF) levels are elevated in SCD… read more here.
Keywords: plgf; placental growth; vaso occlusive; cell disease ... See more keywords
Levels of angiogenic markers in second-trimester maternal serum from in vitro fertilization pregnancies with oocyte donation.
Sign Up to like & getrecommendations! Published in 2019 at "Fertility and sterility"
DOI: 10.1016/j.fertnstert.2019.07.017
Abstract: OBJECTIVE To determine whether differences exist in angiogenic placental growth factor (PlGF) and antiangiogenic soluble vascular endothelial growth factor receptor 1 (sVEGFR-1; both being early markers of placental ischemic disease) in oocyte-donation (OD) pregnancies, compared… read more here.
Keywords: pregnancy; plgf; oocyte donation; second trimester ... See more keywords
The Association between Maternal Placental Growth Factor and Placental Maternal Vascular Malperfusion Lesions.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of gynecology obstetrics and human reproduction"
DOI: 10.1016/j.jogoh.2021.102179
Abstract: INTRODUCTION Placental Growth Factor (PlGF) is used for the prediction of preeclampsia (PE), a syndrome associated with maternal vascular malperfusion (MVM). Our goal is to determine the correlation between PlGF and MVM. MATERIAL AND METHODS… read more here.
Keywords: plgf; placental growth; mvm; growth factor ... See more keywords
Tumor necrosis factor-α regulates angiogenesis of BeWo cells via synergy of PlGF/VEGFR1 and VEGF-A/VEGFR2 axes.
Sign Up to like & getrecommendations! Published in 2018 at "Placenta"
DOI: 10.1016/j.placenta.2018.12.009
Abstract: OBJECTIVES Tumor necrosis factor-alpha (TNF- α) promotes tumor growth by enhancing tumor angiogenesis; however, the effects on choriocarcinoma remain unknown. We investigated the effects of TNF-α on the production of placental growth factor (PlGF) and… read more here.
Keywords: vegf; plgf; bewo cells; vegfr1 ... See more keywords
Reference centiles for maternal placental growth factor levels at term from a low-risk population.
Sign Up to like & getrecommendations! Published in 2019 at "Placenta"
DOI: 10.1016/j.placenta.2019.08.086
Abstract: INTRODUCTION Placental growth factor (PLGF) is a biomarker of placental function. The aim of this study was to define reference ranges for maternal PLGF levels in a normotensive cohort ≥36 + 0 weeks. METHOD Prospective observational data… read more here.
Keywords: term; plgf; placental growth; plgf levels ... See more keywords
96. Effect of preventative treatment with placental growth factor-2 on experimental preeclampsia induced by TNF-α in pregnant mice
Sign Up to like & getrecommendations! Published in 2018 at "Pregnancy Hypertension"
DOI: 10.1016/j.preghy.2018.08.064
Abstract: Introduction Placental growth factor (PlGF) is deficient in women with preeclampsia and treatment of experimental preeclampsia (EPE) with parenteral PlGF has been successful in animal models. Abnormal placentation is thought to be the initiating event… read more here.
Keywords: plgf; treatment; preeclampsia; preventative treatment ... See more keywords
Inter-manufacturer comparison of automated immunoassays for the measurement of soluble FMS-like tyrosine kinase-1 and placental growth factor.
Sign Up to like & getrecommendations! Published in 2019 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2019.06.004
Abstract: OBJECTIVE To assess inter-manufacturer automated immunoassays for soluble FMS-like tyrosine kinase 1 (sFlt-1) to placental growth factor (PlGF). METHODS sFlt-1 and PlGF levels were measured using the AutoDelfia PlGF1-2-3 (PerkinElmer Inc. Turku, Finland), BRAHMS Kryptor… read more here.
Keywords: inter manufacturer; sflt plgf; plgf;
Correlation of Kryptor and Elecsys® immunoassay sFlt-1/PlGF ratio on early diagnosis of preeclampsia and fetal growth restriction: A case-control study.
Sign Up to like & getrecommendations! Published in 2020 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2020.03.002
Abstract: OBJECTIVES The measurement of the soluble fms-like tyrosine kinase-1 to placental growth factor (sFlt-1/PlGF) ratio on automated platforms has improved the detection of preeclampsia and fetal growth restriction (PE/FGR). The cut-off points of >38 and… read more here.
Keywords: plgf; sflt plgf; plgf ratio; growth ... See more keywords