Articles with "plin2" as a keyword



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Muscle‐specific Perilipin2 down‐regulation affects lipid metabolism and induces myofiber hypertrophy

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Published in 2019 at "Journal of Cachexia, Sarcopenia and Muscle"

DOI: 10.1002/jcsm.12355

Abstract: Perilipin2 (Plin2) belongs to a family of five highly conserved proteins, known for their role in lipid storage. Recent data indicate that Plin2 has an important function in cell metabolism and is involved in several… read more here.

Keywords: metabolism; muscle; plin2; specific perilipin2 ... See more keywords
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HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila.

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Published in 2017 at "Developmental cell"

DOI: 10.1016/j.devcel.2017.09.001

Abstract: Age-dependent ectopic fat accumulation (EFA) in animals contributes to the progression of tissue aging and diseases such as obesity, diabetes, and cancer. However, the primary causes of age-dependent EFA remain largely elusive. Here, we characterize… read more here.

Keywords: age dependent; age; proteostasis; plin2 ... See more keywords
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Reactive Oxygen Species Induces Lipid Droplet Accumulation in HepG2 Cells by Increasing Perilipin 2 Expression

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Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19113445

Abstract: Non-alcoholic fatty liver disease (NAFLD) has become the world’s most common liver disease. The disease can develop liver fibrosis or even carcinomas from the initial hepatic steatosis, and this process is influenced by many factors.… read more here.

Keywords: accumulation; droplet; plin2; hepg2 cells ... See more keywords
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Overexpression of PLIN2 is a prognostic marker and attenuates tumor progression in clear cell renal cell carcinoma

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Published in 2018 at "International Journal of Oncology"

DOI: 10.3892/ijo.2018.4384

Abstract: Clear cell renal cell carcinoma (ccRCC) is the most common renal malignancy in adults, the incidence of which continues to increase. The lipid droplet protein perilipin 2 (PLIN2), which was originally considered an RNA transcript,… read more here.

Keywords: cell renal; ccrcc; plin2; expression ... See more keywords