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Published in 2018 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2018.05.023
Abstract: Polo-like kinase-1 (PLK-1) plays a key role in cell cycle progression during mitosis. Overexpression/dysfunction of PLK-1 is directly associated with cancerous transformation and has been reported in different cancer types. Here, we employed high throughput…
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Keywords:
like kinase;
kinase;
polo like;
hesperidin ... See more keywords
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Published in 2023 at "Molecules"
DOI: 10.3390/molecules28062550
Abstract: PLK-1 (Polo-like kinase-1) plays an essential role in cytokinesis, and its aberrant expression is considered to be keenly associated with a wide range of cancers. It has been selected as an appealing target and small-molecule…
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Keywords:
orbitrap hrms;
compound;
plk inhibitors;
uhplc orbitrap ... See more keywords