Study on Pharmacokinetics and Metabolic Profiles of Novel Potential PLK-1 Inhibitors by UHPLC-MS/MS Combined with UHPLC-Q-Orbitrap/HRMS
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DOI: 10.3390/molecules28062550
Abstract: PLK-1 (Polo-like kinase-1) plays an essential role in cytokinesis, and its aberrant expression is considered to be keenly associated with a wide range of cancers. It has been selected as an appealing target and small-molecule… read more here.
Keywords: orbitrap hrms; compound; plk inhibitors; uhplc orbitrap ... See more keywords