Characteristics and prognostic significance of polo-like kinase-1 (PLK1) expression in breast cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Histopathology"
DOI: 10.1111/his.14960
Abstract: AIM Polo-like kinase-1 (PLK1) plays a crucial role in cell cycle progression, and it is considered a potential therapeutic target in many cancers. Although the role of PLK1 is well established in triple-negative breast cancer… read more here.
Keywords: polo like; plk1; role; expression ... See more keywords
Clinicopathological Significance of AKT1 and PLK1 Expression in Oral Squamous Cell Carcinoma
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DOI: 10.1155/2022/7300593
Abstract: Purpose Oral squamous cell carcinoma (OSCC) is the sixth leading cause of cancer-related death worldwide and is characterized by metastasis and recurrence. We aimed to evaluate the expression of AKT1 and PLK1 in OSCC and… read more here.
Keywords: akt1 plk1; plk1 expression; correlation; expression ... See more keywords
Abstract PS2-01: Plk1 expression & efficacy of palbociclib in advanced hormonal receptor-positive breast cancer patients from PEARL study (GEICAM 2012-03)
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DOI: 10.1158/1538-7445.sabcs20-ps2-01
Abstract: Background: CDK 4/6 inhibitors (CDK 4/6i) with endocrine therapy (ET) combination therapy have improved outcomes in patients (pts) with hormonal receptor positive (HR+)/human epidermal growth factor receptor negative (HER2-) advanced breast cancer (ABC). However, most… read more here.
Keywords: plk1; plk1 expression; cancer; receptor ... See more keywords
Pan-Cancer Transcriptomic Analysis Identifies PLK1 Crucial for the Tumorigenesis of Clear Cell Renal Cell Carcinoma
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DOI: 10.2147/jir.s347732
Abstract: Background Polo-like kinase 1 (PLK1) belongs to polo-like kinases family and affects cell cycles. However, the role of PLK1 in some malignant tumors remains unclear. Methods To obtain a comprehensive view of PLK1 expression patterns,… read more here.
Keywords: cell; clear cell; cancer; plk1 expression ... See more keywords
SETD3 Methyltransferase Regulates PLK1 Expression to Promote In Situ Hepatic Carcinogenesis
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DOI: 10.3389/fonc.2022.882202
Abstract: Background The development of a new strategy to overcome chemoresistance to hepatocellular carcinoma (HCC) treatment is a long-standing issue. We have previously found that upregulated SETD3 levels are closely correlated with HCC. This study aims… read more here.
Keywords: cell; expression; setd3; hepatic carcinogenesis ... See more keywords