Articles with "plk1 mediated" as a keyword



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PLK1-mediated phosphorylation of PPIL2 regulates HR via CtIP

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.902403

Abstract: Homologous recombination (HR) is an error-free DNA double-strand break (DSB) repair pathway, which safeguards genome integrity and cell viability. Human C-terminal binding protein (CtBP)—interacting protein (CtIP) is a central regulator of the pathway which initiates… read more here.

Keywords: dna; plk1 mediated; ctip; ppil2 ... See more keywords
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Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27154867

Abstract: Deciphering the protein posttranslational modification (PTM) code is one of the greatest biochemical challenges of our time. Phosphorylation and ubiquitylation are key PTMs that dictate protein function, recognition, sub-cellular localization, stability, turnover and fate. Hence,… read more here.

Keywords: mediated phosphorylation; plk1 mediated; antibody serine; phosphorylated ubiquitin ... See more keywords