Articles with "plk1 polo" as a keyword



Inhibitors of the PLK1 polo-box domain: drug design strategies and therapeutic opportunities in cancer

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Published in 2022 at "Expert Opinion on Drug Discovery"

DOI: 10.1080/17460441.2023.2159942

Abstract: ABSTRACT Introduction Polo Like Kinase 1 (PLK1) is a key regulator of mitosis and its overexpression is frequently observed in a wide variety of human cancers, while often being associated with poor survival rates. Therefore,… read more here.

Keywords: pbd; polo box; inhibitors plk1; plk1 polo ... See more keywords