Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.09.008
Abstract: Glioblastoma (GBM) is the deadliest primary brain tumor that is highly resistant to current treatments. Polo-like kinase 1 (PLK1) and signal transducer and activator of transcription 3 (STAT3) are highly expressed in gliomas, especially GBM.… read more here.
Keywords: plk1; apoptosis; dual plk1; inhibition ... See more keywords