Histone Deacetylase SIRT1 Targets Plk2 to Regulate Centriole Duplication.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.11.025
Abstract: The protein deacetylase SIRT1 (Sirtuin 1) regulates many cellular processes, including cell-cycle progression, DNA damage response, and metabolism. Although the centrosome is a key regulator of cell-cycle progression and genome stability, little is known concerning… read more here.
Keywords: sirt1; deacetylase sirt1; centriole duplication; plk2 ... See more keywords
Polo-Like Kinase 2: From Principle to Practice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.956225
Abstract: Polo-like kinase (PLK) 2 is an evolutionarily conserved serine/threonine kinase that shares the n-terminal kinase catalytic domain and the C-terminal Polo Box Domain (PBD) with other members of the PLKs family. In the last two… read more here.
Keywords: polo like; like kinase; kinase; principle practice ... See more keywords