Articles with "plk4 activation" as a keyword



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Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly

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Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-04122-x

Abstract: Centrosomes are required for faithful chromosome segregation during mitosis. They are composed of a centriole pair that recruits and organizes the microtubule-nucleating pericentriolar material. Centriole duplication is tightly controlled in vivo and aberrations in this… read more here.

Keywords: centriole assembly; plk4 activation; centriole;