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   Articles with "pln" as a keyword



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Impact of daily soft‐tissue image guidance to prostate on pelvic lymph node (PLN) irradiation for prostate patients receiving SBRT

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recommendations! Published in 2019 at "Journal of Applied Clinical Medical Physics"

DOI: 10.1002/acm2.12665

Abstract: Abstract Purpose To determine the impact of using fiducial match for daily image‐guidance on pelvic lymph node (PLN) coverage for prostate cancer patients receiving stereotactic body radiation therapy (SBRT). Methods Thirty patients underwent SBRT treatment… read more here.

Keywords: prostate; pln; pelvic lymph; volume ... See more keywords
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Liposome‐induced immunosuppression and tumor growth is mediated by macrophages and mitigated by liposome‐encapsulated alendronate☆

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recommendations! Published in 2018 at "Journal of Controlled Release"

DOI: 10.1016/j.jconrel.2017.12.023

Abstract: ABSTRACT Liposomal nanoparticles are the most commonly used drug nano‐delivery platforms. However, recent reports show that certain pegylated liposomal nanoparticles (PLNs) and polymeric nanoparticles have the potential to enhance tumor growth and inhibit antitumor immunity… read more here.

Keywords: pln; tumor; alendronate; immunosuppression ... See more keywords
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-AChR is partly responsible in mice depressive-like behavior after Phosalone exposure.

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recommendations! Published in 2021 at "Neurotoxicology and teratology"

DOI: 10.1016/j.ntt.2021.106957

Abstract: BACKGROUND Phosalone (Pln) is an organophosphorus pesticide acetylcholinesterase (AChE) inhibitor. Blockade of AChE amplifies ACh signaling that is related to depressive symptoms. The effects of Pln exposure were evaluated on depressive behavior in mice and… read more here.

Keywords: pln; exposure; behavior; immobility time ... See more keywords
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Copper-Plumbagin Complex Produces Potent Anticancer Effects by Depolymerizing Microtubules and Inducing Reactive Oxygen Species and DNA Damage

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recommendations! Published in 2023 at "ACS Omega"

DOI: 10.1021/acsomega.2c06691

Abstract: Here, we have synthesized a copper complex of plumbagin (Cu-PLN) and investigated its antiproliferative activities in different cancer cells. The crystal structure of Cu-PLN showed that the complex was square planar with a binding stoichiometry… read more here.

Keywords: reactive oxygen; copper; oxygen species; plumbagin ... See more keywords
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Phospholamban pentamerization increases sensitivity and dynamic range of cardiac relaxation.

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recommendations! Published in 2023 at "Cardiovascular research"

DOI: 10.1093/cvr/cvad037

Abstract: AIMS A key event in the regulation of cardiac contraction and relaxation is the phosphorylation of phospholamban (PLN) that relieves the inhibition of the sarco/endoplasmic Ca2+-ATPase SERCA2a. PLN exists in an equilibrium between monomers and… read more here.

Keywords: tgafa pln; pln pentamerization; relaxation; pentamerization ... See more keywords
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Leducq Transatlantic Network of Excellence to Cure Phospholamban-Induced Cardiomyopathy (CURE-PLaN).

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recommendations! Published in 2019 at "Circulation Research"

DOI: 10.1161/circresaha.119.315077

Abstract: The deletion of Arginine 14 of the phosholamban gene (PLN p.R14del) is associated with the pathogenesis of an inherited form of cardiomyopathy with prominent arrhythmias. Patients carrying the PLN R14del mutation are at risk of… read more here.

Keywords: cure plan; cure; pln; network ... See more keywords
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Nanoincorporation of Plumbagin in Micelles Increase Its in Vivo Anti-Plasmodial Properties

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recommendations! Published in 2022 at "Iranian Journal of Parasitology"

DOI: 10.18502/ijpa.v17i2.9538

Abstract: Background: The application of plumbagin (PLN), with a wide use in pharmaceutical science, is limited due to its low water solubility and poor bioavailability. Micelles can encapsulate hydrophobic drugs due to their hydrophobic core. The… read more here.

Keywords: anti plasmodial; vivo anti; drug; plumbagin ... See more keywords
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Salmonella in Peripheral Lymph Nodes of Healthy Cattle at Slaughter

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recommendations! Published in 2017 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2017.02214

Abstract: To more fully characterize the burden of Salmonella enterica in bovine peripheral lymph nodes (PLN), PLN (n = 5,450) were collected from healthy cattle at slaughter in 12 commercial abattoirs that slaughtered feedlot-fattened (FF) cattle… read more here.

Keywords: pln; salmonella; lymph nodes; prevalence ... See more keywords
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Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca2+ and phosphorylation

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recommendations! Published in 2021 at "eLife"

DOI: 10.7554/elife.66226

Abstract: Phospholamban (PLN) is a mini-membrane protein that directly controls the cardiac Ca2+-transport response to β-adrenergic stimulation, thus modulating cardiac output during the fight-or-flight response. In the sarcoplasmic reticulum membrane, PLN binds to the sarco(endo)plasmic reticulum… read more here.

Keywords: phosphorylation; membrane; basis allosteric; ca2 ... See more keywords