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   Articles with "plod2" as a keyword



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Pan-Cancer Analyses Reveal Oncogenic and Immunological Role of PLOD2

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recommendations! Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.864655

Abstract: Some previous studies have shown that PLOD2 has some value in tumorigenesis. However, the broad significance of PLOD2 has not been discussed in depth. This study was aimed at elaborated and summarized the value of… read more here.

Keywords: role; plod2; pan cancer; expression ... See more keywords
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PLOD2 high expression associates with immune infiltration and facilitates cancer progression in osteosarcoma

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.980390

Abstract: Background Osteosarcoma (OS) is the most common primary malignant bone tumors in children and adolescents. Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (PLOD2) is a key gene in mediating the formation of the stabilized collagen cross-link, playing an… read more here.

Keywords: infiltration; plod2 high; immune infiltration; plod2 ... See more keywords
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PLOD2 Is a Prognostic Marker in Glioblastoma That Modulates the Immune Microenvironment and Tumor Progression

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23116037

Abstract: This study aimed to investigate the role of Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 2 (PLOD2) in glioblastoma (GBM) pathophysiology. To this end, PLOD2 protein expression was assessed by immunohistochemistry in two independent cohorts of patients with primary… read more here.

Keywords: log rank; glioblastoma; plod2; progression ... See more keywords
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PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1

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recommendations! Published in 2021 at "International Journal of Oncology"

DOI: 10.3892/ijo.2021.5209

Abstract: We previously reported that high expression of procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 (PLOD2) leads to stabilization and plasma membrane translocation of integrin β1 to promote the invasion and metastasis of oral squamous cell carcinoma (SCC). The… read more here.

Keywords: plod2; expression; metastasis oral; invasion metastasis ... See more keywords