A β1-tubulin-based megakaryocyte maturation reporter system identifies novel drugs that promote platelet production.
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DOI: 10.1182/bloodadvances.2018019547
Abstract: During maturation, megakaryocytes (MKs) express β1-tubulin (TUBB1) and rearrange their microtubule components to enlarge, form proplatelets, and eventually release platelets. The development of a platform to identify in vitro conditions that would efficiently promote MK… read more here.
Keywords: reporter; production; plp production; platelet production ... See more keywords