Effect of Dupilumab on Mucus Burden in Patients with Moderate-to-Severe Asthma: The VESTIGE Trial.
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DOI: 10.1164/rccm.202410-1894oc
Abstract: RATIONALE Chronic mucus hypersecretion contributes to airway obstruction in asthma. OBJECTIVES Assess dupilumab efficacy by baseline mucus plug score. METHODS In VESTIGE (NCT04400318), adults with moderate-to-severe asthma, baseline blood eosinophils ≥300 cells/μL, and fractional exhaled… read more here.
Keywords: moderate severe; plug score; mucus plug; mucus ... See more keywords