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Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2021.0347
Abstract: Cellular metabolism plays both an active and passive role in embryonic development, pluripotency, and cell-fate decisions. However, little is known regarding the role of metabolism in regulating the recently described "formative" pluripotent state. The pluripotent…
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Keywords:
pkm1;
stem cells;
pluripotent state;
state ... See more keywords
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Published in 2022 at "Cell Proliferation"
DOI: 10.1111/cpr.13195
Abstract: Spermatogonial stem cells (SSCs), the germline stem cells (GSCs) committed to spermatogenesis in niche, can transform into pluripotent state in longāterm culture without introduction of exogenous factors, typically in p53 deficiency condition. As the guardian…
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Keywords:
pluripotent state;
stem cells;
spermatogonial stem;
stem ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054862
Abstract: The monoamine neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has important functions both in the neural system and during embryonic development in mammals. In this study, we set out to investigate whether and how endogenous serotonin affects reprogramming…
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Keywords:
serotonin biosynthesis;
pluripotent state;
tryptophan hydroxylase;