SAT0360 A summary of clinical evidence for commonly used uricosurics for gout in europe
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DOI: 10.1136/annrheumdis-2018-eular.3026
Abstract: Background Uricosurics (benzbromarone, probenecid, or sulfinpyrazone) are recommended for second-line treatment of gout if treatment target cannot be achieved with allopurinol or if allopurinol cannot be tolerated. While some uricosurics have been available since the… read more here.
Keywords: quality; summary clinical; evidence; plus allopurinol ... See more keywords
Pharmacodynamic and pharmacokinetic effects and safety of verinurad in combination with allopurinol in adults with gout: a phase IIa, open-label study
Sign Up to like & getrecommendations! Published in 2018 at "RMD Open"
DOI: 10.1136/rmdopen-2017-000584
Abstract: Objectives Verinurad (RDEA3170) is a high affinity, selective uric acid transporter (URAT1) inhibitor indevelopment for treating gout and asymptomatic hyperuricaemia. This phase IIa study evaluated the pharmacodynamics, pharmacokinetics and safety of verinurad combined with allopurinol… read more here.
Keywords: verinurad; adults gout; safety verinurad; phase iia ... See more keywords